Cardiovascular risk status of Afro-origin populations across the spectrum of economic development: findings from the Modeling the Epidemiologic Transition Study
| العنوان: | Cardiovascular risk status of Afro-origin populations across the spectrum of economic development: findings from the Modeling the Epidemiologic Transition Study |
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| المؤلفون: | Richard S. Cooper, Ramon Durazo-Arvizu, Lara R. Dugas, Laura Tonino, Jacob Plange-Rhule, Wolfgang Korte, Walter F. Riesen, Estelle V. Lambert, Amy Luke, Stephanie Kliethermes, Pascal Bovet, Guichan Cao, Terrence Forrester, Rasha Khatib |
| المساهمون: | MRC/UCT RU for Exercise and Sport Medicine, Faculty of Health Sciences, Division of Exercise Science and Sports Medicine |
| المصدر: | BMC Public Health BMC public health, vol. 17, no. 1, pp. 438 BMC Public Health, Vol 17, Iss 1, Pp 1-9 (2017) |
| بيانات النشر: | BioMed Central, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Adult, Male, Human development index, Jamaica, Economic growth, medicine.medical_specialty, Population, Black People, Developing country, 030204 cardiovascular system & hematology, Seychelles, Ghana, African diaspora, South Africa, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Epidemiology, Prevalence, Humans, Medicine, 030212 general & internal medicine, Risk factor, education, Developing Countries, African Continental Ancestry Group, Chicago, education.field_of_study, Framingham Risk Score, business.industry, lcsh:Public aspects of medicine, 1. No poverty, Public Health, Environmental and Occupational Health, lcsh:RA1-1270, Middle Aged, medicine.disease, Cardiovascular risk, Obesity, 3. Good health, Europe, Epidemiologic Studies, Epidemiological transition, Socioeconomic Factors, Cardiovascular Diseases, Female, Economic Development, Biostatistics, business, Research Article |
| الوصف: | Background Cardiovascular risk factors are increasing in most developing countries. To date, however, very little standardized data has been collected on the primary risk factors across the spectrum of economic development. Data are particularly sparse from Africa. Methods In the Modeling the Epidemiologic Transition Study (METS) we examined population-based samples of men and women, ages 25–45 of African ancestry in metropolitan Chicago, Kingston, Jamaica, rural Ghana, Cape Town, South Africa, and the Seychelles. Key measures of cardiovascular disease risk are described. Results The risk factor profile varied widely in both total summary estimates of cardiovascular risk and in the magnitude of component factors. Hypertension ranged from 7% in women from Ghana to 35% in US men. Total cholesterol was well under 200 mg/dl for all groups, with a mean of 155 mg/dl among men in Ghana, South Africa and Jamaica. Among women total cholesterol values varied relatively little by country, following between 160 and 178 mg/dl for all 5 groups. Levels of HDL-C were virtually identical in men and women from all study sites. Obesity ranged from 64% among women in the US to 2% among Ghanaian men, with a roughly corresponding trend in diabetes. Based on the Framingham risk score a clear trend toward higher total risk in association with socioeconomic development was observed among men, while among women there was considerable overlap, with the US participants having only a modestly higher risk score. Conclusions These data provide a comprehensive estimate of cardiovascular risk across a range of countries at differing stages of social and economic development and demonstrate the heterogeneity in the character and degree of emerging cardiovascular risk. Severe hypercholesterolemia, as characteristic in the US and much of Western Europe at the onset of the coronary epidemic, is unlikely to be a feature of the cardiovascular risk profile in these countries in the foreseeable future, suggesting that stroke may remain the dominant cardiovascular event. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| DOI: | 10.1186/s12889-017-4318-4 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99c1608f1f4dabf6c74e1a7bd1efc79Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c99c1608f1f4dabf6c74e1a7bd1efc79 |
| قاعدة البيانات: | OpenAIRE |
| DOI: | 10.1186/s12889-017-4318-4 |
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