Plasma Atrial Natriuretic Peptide in Essential Hypertension after Treatment with Irbesartan
| العنوان: | Plasma Atrial Natriuretic Peptide in Essential Hypertension after Treatment with Irbesartan |
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| المؤلفون: | Olga Gouli, George Dadous, Michalis Karamouzis, Pavlos C. Papadopoulos, Ioannis Kanonidis, P. Kotridis, Basile Kokkas, C.L. Papadopoulos, G. Sakadamis, Chrisoula Karantona, Joshef Karadoumanis |
| المصدر: | Blood Pressure. 11:91-94 |
| بيانات النشر: | Informa UK Limited, 2002. |
| سنة النشر: | 2002 |
| مصطلحات موضوعية: | Adult, Male, Drug, medicine.medical_specialty, media_common.quotation_subject, medicine.medical_treatment, Tetrazoles, Blood Pressure, Essential hypertension, Receptor, Angiotensin, Type 1, Angiotensin Receptor Antagonists, Irbesartan, Atrial natriuretic peptide, Oral administration, Internal medicine, Internal Medicine, medicine, Humans, Antihypertensive Agents, Aged, media_common, Chemotherapy, business.industry, Biphenyl Compounds, General Medicine, Middle Aged, medicine.disease, Angiotensin II, Endocrinology, Blood pressure, Hypertension, cardiovascular system, Cardiology and Cardiovascular Medicine, business, Atrial Natriuretic Factor, medicine.drug |
| الوصف: | The aim of this study was to evaluate the medium-term effects of the selective AT 1 -blocker irbesartan on atrial natriuretic peptide (ANP) levels in patients with moderate essential hypertension. The drug was given orally in a daily dose of 300 mg for 30 days. Plasma ANP levels increased by 15.7% despite the drop in blood pressure and the slight decrease of atrial and ventricular diameters. These findings indicate that AT 1 -blockers like irbesartan exert part of their antihypertensive action by increasing ANP plasma levels. |
| تدمد: | 1651-1999 0803-7051 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72166ab421bf1d43a060df92e4c5783Test https://doi.org/10.1080/08037050211263Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c72166ab421bf1d43a060df92e4c5783 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16511999 08037051 |
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