Analysis of Endothelin-1 Concentrations in Individuals with Periodontitis
| العنوان: | Analysis of Endothelin-1 Concentrations in Individuals with Periodontitis |
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| المؤلفون: | Francesco Indelicato, Alessandro Polizzi, Gaetano Isola, Angela Alibrandi, Sebastiano Ferlito |
| المصدر: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020) |
| بيانات النشر: | Nature Publishing Group UK, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Saliva, Multivariate analysis, Endothelium, lcsh:Medicine, Coronary Disease, 02 engineering and technology, Gastroenterology, Article, 03 medical and health sciences, 0302 clinical medicine, Medical research, Internal medicine, medicine, Oral diseases, Humans, lcsh:Science, Periodontitis, Multidisciplinary, Endothelin-1, business.industry, lcsh:R, Case-control study, 030206 dentistry, Middle Aged, 021001 nanoscience & nanotechnology, medicine.disease, Serum samples, Endothelin 1, Coronary heart disease, medicine.anatomical_structure, C-Reactive Protein, Case-Control Studies, Multivariate Analysis, lcsh:Q, Female, Inflammation Mediators, 0210 nano-technology, business, Biomarkers |
| الوصف: | Endothelin 1 (ET-1) has been shown to have a key role in homeostasis and function of endothelium and maybe fundamental in the relationship between coronary heart disease (CHD) and periodontitis. In this trial, we assessed the influence on serum and salivary ET-1 levels of gingival health, CHD, periodontitis, or a combination of periodontitis-CHD. Clinical and periodontal parameters, were collected from periodontitis patients (n = 34), CHD patients (n = 34), periodontitis + CHD patients (n = 34), and from healthy patients (n = 34) together with saliva and serum samples. The median concentrations of salivary and serum ET-1 were significantly higher in the CHD patients [serum: 1.4(1.1–1.6) pg/ml; saliva 1.2 (0.9–1.6) µmol/g, p |
| اللغة: | English |
| تدمد: | 2045-2322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b40518f6c4ce66808481e301a99f58Test http://europepmc.org/articles/PMC6997234Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c6b40518f6c4ce66808481e301a99f58 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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