Healthcare-associated Infections in Pediatric Patients in Neurotrauma Intensive Care Unit: A Retrospective Analysis
| العنوان: | Healthcare-associated Infections in Pediatric Patients in Neurotrauma Intensive Care Unit: A Retrospective Analysis |
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| المؤلفون: | Purva Mathur, Pankaj Kumar Singh, Chandrakant Prasad, Gyaninder Pal Singh, Parul Singh, Ashish Bindra |
| المصدر: | Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine |
| بيانات النشر: | Jaypee Brothers Medical Publishing, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Pediatric, Healthcare associated infections, Pediatric Critical Care, medicine.medical_specialty, Traumatic brain injury, business.industry, Critical Care and Intensive Care Medicine, medicine.disease, Trauma, Intensive care unit, law.invention, law, Emergency medicine, medicine, Retrospective analysis, Healthcare-associated infection, business |
| الوصف: | Background Healthcare-associated infections (HAIs) can impact the outcome following traumatic brain injury (TBI) in children. We undertook a retrospective observational study to see the incidence, risk factors, and microbiological profile for HAIs in pediatric TBI. We also studied the impact of baseline patient characteristics, HAIs on patient outcome, and antibiotic resistance of different types of bacteria. Materials and methods Data on pediatric TBI patients of age up to 12 years were collected via a computerized patient record system (CPRS) from January 2012 to December 2018. Descriptive Chi-square test and Wilcoxon signed rank test were used to characterize baseline parameters. General linear regression models were run to find an unadjusted and adjusted odds ratio (OR). Results HAIs were found in 144 (34%) out of 423 patients. The most commonly seen infections were of the respiratory tract in 73 (17.26%) subjects. The most predominant microorganism isolated was Acinetobacter baumannii in 188 (41%) samples. A. baumannii was sensitive to colistin in 91 (48.4%) patients. Male gender (OR 0.630; p-value 0.035), fall from height (OR 0.374; p-value 0.008), and higher injury severity scale (ISS) (OR 1.040; p-value 0.002) were independent risk factors for development of HAIs. Severe TBI, higher ISS and Marshall grade, and HAIs were significantly associated with poor patient outcome. Conclusion Severe TBI poses a significant risk of HAIs. The most common site was the respiratory tract, predominately infected with A. baumannii. HAIs in pediatric TBI patients resulted in poor patient outcome. How to cite this article Prasad C, Bindra A, Singh P, Singh GP, Singh PK, Mathur P. Healthcare-associated Infections in Pediatric Patients in Neurotrauma Intensive Care Unit: A Retrospective Analysis. Indian J Crit Care Med 2021;25(11):1308–1313. |
| تدمد: | 1998-359X 0972-5229 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ce559173031d31167ffcc9839a3070Test https://doi.org/10.5005/jp-journals-10071-24012Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c3ce559173031d31167ffcc9839a3070 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1998359X 09725229 |
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