Islet growth and development in the adult
| العنوان: | Islet growth and development in the adult |
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| المؤلفون: | Susan Bonner-Weir |
| المصدر: | Journal of Molecular Endocrinology. 24:297-302 |
| بيانات النشر: | Bioscientifica, 2000. |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | Adult, medicine.medical_specialty, endocrine system diseases, Apoptosis, Disease, Carbohydrate metabolism, Islets of Langerhans, Endocrinology, Insulin resistance, Diabetes mellitus, Internal medicine, Acromegaly, medicine, Animals, Humans, Molecular Biology, geography, geography.geographical_feature_category, business.industry, nutritional and metabolic diseases, medicine.disease, Islet, Obesity, Diabetes Mellitus, Type 1, Glucose, Diabetes Mellitus, Type 2, Insulin Resistance, business, Cell Division, Cell mass |
| الوصف: | Diabetes mellitus, whether type 1 (insulindependent diabetes mellitus; IDDM) or type 2 (noninsulin-dependent diabetes mellitus; NIDDM) results from an inadequate mass of functional pancreatic -cells. In the first case, the -cell mass is reduced by the autoimmune destruction of the -cells, while, in the latter, there is incomplete compensation to meet the demand often imposed by insulin resistance. This latter point is not always appreciated. However, only 20% of those people with severe insulin resistance due to obesity, Cushing’s disease, or acromegaly become diabetic, with the other 80% being able to compensate to |
| تدمد: | 1479-6813 0952-5041 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c3b33ad73e00761e4b5ba8170f866bTest https://doi.org/10.1677/jme.0.0240297Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c2c3b33ad73e00761e4b5ba8170f866b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14796813 09525041 |
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