In vivo time-resolved reflectance spectroscopy of the human forehead
| العنوان: | In vivo time-resolved reflectance spectroscopy of the human forehead |
|---|---|
| المؤلفون: | Antonio Pifferi, Giovanni Zaccanti, Andrea Bassi, Alessandro Torricelli, Daniela Comelli, Paola Taroni, Fabrizio Martelli, Rinaldo Cubeddu |
| المصدر: | Applied optics 46 (2007): 1717–1725. info:cnr-pdr/source/autori:D. Comelli, A. Bassi, A. Pifferi, P. Taroni, A. Torricelli, R. Cubeddu, F. Martelli, G. Zaccanti/titolo:In vivo time-resolved reflectance spectroscopy of the human forehead/doi:/rivista:Applied optics/anno:2007/pagina_da:1717/pagina_a:1725/intervallo_pagine:1717–1725/volume:46 |
| سنة النشر: | 2007 |
| مصطلحات موضوعية: | Adult, Male, Materials science, Spectrophotometry, Infrared, Absorption spectroscopy, Materials Science (miscellaneous), Monte Carlo method, TISSUE OPTICAL-PROPERTIES, NONINVASIVE DETERMINATION, Models, Biological, Industrial and Manufacturing Engineering, Optics, Image Interpretation, Computer-Assisted, Humans, Computer Simulation, Forehead, Business and International Management, Spectroscopy, Human head, Phantoms, Imaging, Scattering, business.industry, ADULT HEAD MODEL, HUMAN BRAIN, NEAR-INFRARED LIGHT, Photon counting, Refractometry, Attenuation coefficient, Female, Time-resolved spectroscopy, business, Algorithms |
| الوصف: | We present an in vivo broadband spectroscopic characterization of the human forehead. Absorption and scattering properties are measured on five healthy volunteers at five different interfiber distances, using time-resolved diffuse spectroscopy and interpreting data with a model of the diffusion equation for a homogeneous semi-infinite medium. A wavelength-tunable mode-locked laser and time-correlated single-photon counting detection are employed, enabling fully spectroscopic measurements in the range of 700-1000 nm. The results show a large variation in the absorption and scattering properties of the head depending on the subject, whereas intrasubject variations, assessed at different interfiber distances, appear less relevant, particularly for what concerns the absorption coefficient. The high intersubject variability observed indicates that a unique set of optical properties for modeling the human bead cannot be used correctly. To better interpret the results of the analysis of in vivo measurements, we performed a set of four-layer model Monte Carlo simulations based on different data sets for the optical properties of the human head, partially derived from the literature. The analysis indicated that, when simulated time-resolved curves are fitted with a homogeneous model for the photon migration, the retrieved absorption and reduced scattering coefficients are much closer to superficial layer values (i.e., scalp and skull) than to deeper layer ones (white and gray matter). In particular, for the shorter interfiber distances, the recovered values can be assumed as a good estimate of the optical properties of the first layer. (c) 2007 Optical Society of America. |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6d5e43652e128262c187763b3bf92eTest http://hdl.handle.net/11311/551882Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bd6d5e43652e128262c187763b3bf92e |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |