Secukinumab demonstrates high efficacy and a favourable safety profile in paediatric patients with severe chronic plaque psoriasis: 52‐week results from a Phase 3 double‐blind randomized, controlled trial
| العنوان: | Secukinumab demonstrates high efficacy and a favourable safety profile in paediatric patients with severe chronic plaque psoriasis: 52‐week results from a Phase 3 double‐blind randomized, controlled trial |
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| المؤلفون: | Külli Kingo, Pascal Charef, E Rivas, Athanasios Tsianakas, Christine Bodemer, S Cafoncelli, P. Papanastasiou, L Zhang, A Kaszuba, Akimichi Morita, Deborah L. Keefe, Charis Papavassilis, Manmath Patekar |
| المصدر: | Journal of the European Academy of Dermatology and Venereology |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, medicine.medical_specialty, Dermatology, Antibodies, Monoclonal, Humanized, Placebo, Severity of Illness Index, Gastroenterology, Etanercept, law.invention, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Randomized controlled trial, law, Internal medicine, Severity of illness, medicine, Psoriasis, Humans, 030212 general & internal medicine, Dosing, Child, Paediatric patients, Plaque psoriasis, business.industry, Antibodies, Monoclonal, Treatment Outcome, Infectious Diseases, Original Article, Secukinumab, business, medicine.drug |
| الوصف: | Background Secukinumab has demonstrated sustained long‐term efficacy with a favourable safety profile in various psoriatic disease manifestations in adults. Objectives Here, the efficacy and safety of two secukinumab dosing regimens [low dose (LD) and high dose (HD)] in paediatric patients with severe chronic plaque psoriasis over one year are reported. Methods In this multicentre, double‐blind study (NCT02471144), patients aged 6 to |
| تدمد: | 1468-3083 0926-9959 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbf195ffa84cbfe415d5fc6c0a4972dTest https://doi.org/10.1111/jdv.17002Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bbbf195ffa84cbfe415d5fc6c0a4972d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14683083 09269959 |
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