Sequential morphological change of Chiari malformation type II following surgical repair of myelomeningocele
| العنوان: | Sequential morphological change of Chiari malformation type II following surgical repair of myelomeningocele |
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| المؤلفون: | Junji Kishimoto, Koji Iihara, Goki Eriguchi, Akio Hiwatashi, Nobuya Murakami, Masayuki Ochiai, Kimiaki Hashiguchi, Osamu Togao, Takato Morioka |
| المصدر: | Child's Nervous System. 32:1069-1078 |
| بيانات النشر: | Springer Science and Business Media LLC, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, Meningomyelocele, Neurosurgical Procedures, 030218 nuclear medicine & medical imaging, Cohort Studies, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Cerebrospinal fluid, Cerebellum, medicine, Humans, Retrospective Studies, Surgical repair, Foramen magnum, Models, Statistical, medicine.diagnostic_test, business.industry, Infant, Newborn, Infant, Magnetic resonance imaging, General Medicine, Anatomy, medicine.disease, Magnetic Resonance Imaging, Arnold-Chiari Malformation, Hydrocephalus, Vertebra, Shunting, Spina Bifida Cystica, medicine.anatomical_structure, Cranial Fossa, Posterior, CHIARI MALFORMATION TYPE II, Pediatrics, Perinatology and Child Health, Female, Neurology (clinical), business, 030217 neurology & neurosurgery |
| الوصف: | To document long-term morphological changes of Chiari type II malformation (CM-II) following closure of spina bifida manifesta (SBM). We retrospectively evaluated postnatal magnetic resonance images of the CM-II and posterior fossa (PF) in 28 consecutive cases. We measured changes in vertebral level and length of the cerebellar peg (CP), cerebrospinal fluid (CSF) spaces anterior and posterior to the cerebrospinal junction, PF area, and the anteroposterior diameters of the foramen magnum (FM) and C1 vertebra. We examined the morphological differences between the cases with and without ventriculoperitoneal (VP) shunting and derived predicted means by nonlinear mixed-effect modeling. At birth, there were significant differences in CP length, PF area, and FM and C1 diameters between those who underwent VP shunting and those who did not. In cases with a CP below C1, VP shunting was required in every case but one. In those with visible CSF space at birth, VP shunts were not required. In 17 of 18 cases with a CP below C1, the vertebral level ascended by mean two vertebral levels (range 0–5 levels) within 4–6 months of delivery. In the remaining case, slowly progressive hydrocephalus and delayed CP descent required VP shunting at 8 months. Predicted mean CP length and FM and C1 diameters were greater in those who underwent VP shunting, but there was no difference in predicted mean PF area. The morphology of CM-II and the presence of hydrocephalus influence each other in children who have undergone postnatal SBM repair. |
| تدمد: | 1433-0350 0256-7040 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6ae1ae92c2ef56db4ab75e9beee324Test https://doi.org/10.1007/s00381-016-3041-2Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....ba6ae1ae92c2ef56db4ab75e9beee324 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14330350 02567040 |
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