Efficacy of a real time optoelectronic device (TruScreen™) in detecting cervical intraepithelial pathologies: a prospective observational study
| العنوان: | Efficacy of a real time optoelectronic device (TruScreen™) in detecting cervical intraepithelial pathologies: a prospective observational study |
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| المؤلفون: | Nuri Danisman, Emre Özgü, Tayfun Gungor, Burçin Salman Özgü, Yunus Yıldız, Murat Oz |
| المصدر: | Journal of the Turkish-German Gynecological Association, Vol 16, Iss 1, Pp 41-44 (2015) |
| بيانات النشر: | Galenos Yayinevi, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Pap smears, Cervical screening, medicine.diagnostic_test, business.industry, lcsh:R, Obstetrics and Gynecology, Papanicolaou stain, lcsh:Medicine, Hpv screening, Cervical cancer screening, lcsh:Gynecology and obstetrics, Cervical biopsy, medicine, Optoelectronics, Observational study, cervical screening, Pap test, cin, business, lcsh:RG1-991, Original Investigation, optoelectronic device |
| الوصف: | Objective To assess the effect of TruScreen™ (an objective optoelectronic cervical screening device) in improving the sensitivity of cervical screening programs either alone or in combination with Papanicolaou (PAP) smear or human papilloma virus (HPV) DNA screening. Material and methods Our study was performed in 285 patients with abnormal Pap test results. TruScreen™ and HPV screening methods were performed in all participants. Consistency and differences between the tests were compared with cervical biopsy results. Results TruScreen™ was found to be an approach method in the determination of cervical pathologies (ROC curve area underlined=0.606) and with an 89.5% negative predictive value. HPV screening remains a counterpart to TruScreen™ with a 0.620 area underlined in the ROC curve and an 83% negative predictive value. Conclusion As determined in our study, TruScreen™ with a sensitivity of 86.1% can be used as a screening test with instant and not professional dependent results for cervical cancer screening. Avoiding from subjectivity in interpretation of Pap smears and requirement for pathologists, TruScreen™ can be a used for cervical cancer screening especially in countries with a low socio-economic status. The combination of TruScreen™ and HPV screening was not able to demonstrate a significant rise of effectiveness in screening. |
| اللغة: | English |
| تدمد: | 1309-0380 1309-0399 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4e50669cfb947051da785e61ad02e5Test https://doaj.org/article/a977691ec85e4d0d94de52ffbd57babcTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ba4e50669cfb947051da785e61ad02e5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13090380 13090399 |
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