Long-Term Metabolic Control with Insulin Pump Therapy
| العنوان: | Long-Term Metabolic Control with Insulin Pump Therapy |
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| المؤلفون: | Edward A. Benson, Robert L. Nielsen, Robert Metz, Robert S. Mecklenburg, Brent A. Blumenstein, Terin S Guinn, James W. Benson, Paul N. Fredlund |
| المصدر: | New England Journal of Medicine. 313:465-468 |
| بيانات النشر: | Massachusetts Medical Society, 1985. |
| سنة النشر: | 1985 |
| مصطلحات موضوعية: | Adult, Male, Insulin pump, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Gastroenterology, Insulin Infusion Systems, Internal medicine, Diabetes mellitus, medicine, Humans, Aged, Glycated Hemoglobin, Chemotherapy, business.industry, Insulin, Conventional treatment, General Medicine, Middle Aged, medicine.disease, Surgery, Diabetes Mellitus, Type 1, Evaluation Studies as Topic, Metabolic control analysis, Type i diabetes, Female, Hemoglobin, business |
| الوصف: | To determine the long-term efficacy of insulin-pump therapy, we analyzed trends in glycosylated hemoglobin concentrations in 127 patients with Type I diabetes using insulin pumps for periods ranging from 13 to 47 months. In the first year of pump therapy the average glycosylated hemoglobin concentration improved in 83 per cent of the patients, as compared with the value before pump therapy. Although only 11 of the 127 subjects had normal glycosylated hemoglobin values before pump therapy, 33 had a normal average value during the first full year of pump use (P = 0.0001). This favorable trend persisted for the three-year duration of the study. Seventeen of the 19 patients who subsequently discontinued insulin-pump therapy had improved glycosylated hemoglobin values during the period of pump use. Eleven of the 19 patients remained available for follow-up study; the glycosylated hemoglobin concentration became worse in 7 when they returned to conventional treatment. We conclude that the improvement in metabolic control repeatedly demonstrated in short-term studies with the insulin pump can be maintained for a period of years. |
| تدمد: | 1533-4406 0028-4793 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e821606ffd3568c0766a039d54c1fcTest https://doi.org/10.1056/nejm198508223130802Test |
| رقم الانضمام: | edsair.doi.dedup.....b7e821606ffd3568c0766a039d54c1fc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15334406 00284793 |
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