Elevated Random Luteinizing Hormone is an Unreliable Indicator for Pubertal Suppression in Girls Treated with Monthly Leuprolide for Idiopathic Central Precocious Puberty
| العنوان: | Elevated Random Luteinizing Hormone is an Unreliable Indicator for Pubertal Suppression in Girls Treated with Monthly Leuprolide for Idiopathic Central Precocious Puberty |
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| المؤلفون: | Ouyporn Panamonta, Pattara Wiromrat |
| المصدر: | JCRPE, Vol 11, Iss 3, Pp 227-233 (2019) Journal of Clinical Research in Pediatric Endocrinology |
| بيانات النشر: | Galenos Yayincilik, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Puberty, Precocious, 030209 endocrinology & metabolism, lcsh:Diseases of the endocrine glands. Clinical endocrinology, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, leuprolide acetate, 030225 pediatrics, Internal medicine, medicine, Humans, In patient, Sexual Maturation, Child, Idiopathic central precocious puberty, Retrospective Studies, lcsh:RC648-665, business.industry, pubertal progression, Body Weight, final adult height, lcsh:RJ1-570, Bone age, lcsh:Pediatrics, Luteinizing Hormone, Central precocious puberty, Prognosis, Adult height, Body Height, monitoring, Pediatrics, Perinatology and Child Health, random luteinizing hormone, Female, Original Article, Leuprolide, Luteinizing hormone, business, After treatment, Clinical progression, Biomarkers, Hormone, Follow-Up Studies |
| الوصف: | Objective: Longitudinal data regarding random luteinizing hormone (LH) concentrations in patients with idiopathic central precocious puberty (ICPP) during treatment are limited. Therefore, we sought to evaluate random LH and estradiol concentrations during monthly leuprolide injection and their associations with pubertal progression and final adult height (FAH) in girls with ICPP. Methods: Medical records of 27 girls with ICPP who had attained FAH were reviewed. Patients’ height, weight, Tanner stage, growth rate (GR), bone age, random LH measured by both immunoradiometric and immunochemiluminescent methods, follicular-stimulating hormone (FSH) and estradiol levels were monitored until FAH. Results: Treatment was started at a mean (±standard deviation) age of 8.1±0.6 years with mean duration of 3.9±0.2 years. At six months of follow-up, random LH (p=0.048), FSH (p |
| اللغة: | English |
| تدمد: | 1308-5735 1308-5727 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20d494f36b4089de17246c1950d5d04Test https://doaj.org/article/9fc1f70a8fbf46b7803944dab70a52e5Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b20d494f36b4089de17246c1950d5d04 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13085735 13085727 |
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