Geographic differences in the prevalence of hypertension in Uganda
| العنوان: | Geographic differences in the prevalence of hypertension in Uganda |
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| المؤلفون: | John W. Stanifer, Robert Kalyesubula, Thys van der Molen, Samuel Kasozi, Bruce Kirenga, Wenceslaus Katagira, Joseph Lunyera, Moses R. Kamya |
| المساهمون: | Groningen Research Institute for Asthma and COPD (GRIAC) |
| المصدر: | PLoS ONE, Vol 13, Iss 8, p e0201001 (2018) PLoS ONE, 13(8):0201001. PUBLIC LIBRARY SCIENCE PLoS ONE |
| بيانات النشر: | PUBLIC LIBRARY SCIENCE, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Cross-sectional study, Social Sciences, lcsh:Medicine, Blood Pressure, 030204 cardiovascular system & hematology, Vascular Medicine, Geographical Locations, 0302 clinical medicine, Sociology, Epidemiology, Prevalence, Medicine and Health Sciences, Uganda, 030212 general & internal medicine, Geography, Medical, Young adult, Child, 10. No inequality, lcsh:Science, SUB-SAHARAN AFRICA, POPULATION, Aged, 80 and over, 2. Zero hunger, education.field_of_study, Schools, Multidisciplinary, Geography, 1. No poverty, Middle Aged, 3. Good health, Professions, CARDIOVASCULAR-DISEASE, Hypertension, Female, Research Article, Adult, medicine.medical_specialty, Adolescent, Population, Education, Young Adult, 03 medical and health sciences, medicine, MANAGEMENT, Humans, education, Educational Attainment, Aged, Asthma, business.industry, lcsh:R, GLOBAL BURDEN, medicine.disease, Confidence interval, Educational attainment, Young Adults, Regional Geography, Cross-Sectional Studies, Blood pressure, Age Groups, People and Places, Africa, Earth Sciences, RISK-FACTORS, Population Groupings, lcsh:Q, business, Demography |
| الوصف: | BackgroundHypertension accounts for more than 212 million global disability-adjusted life-years, and more than 15 million in sub-Saharan Africa. Identifying factors underlying the escalating burden of hypertension in sub-Saharan Africa may inform delivery of targeted public health interventions.MethodsAs part of the cross-sectional nationally representative Uganda National Asthma Survey conducted in 2016, we measured blood pressure (BP) in the general population across five regions of Uganda. We defined hypertension as systolic BP >= 140 mmHg and/or diastolic BP >= 90 mmHg, or on-going use of medications for the purpose of lowering BP among adults (>= 18 years of age); pre-hypertension as systolic BP between 120 and 140 mmHg and/or diastolic BP bteween 80 and 90 mmHg among adolescents and adults (>= 12 years of age).FindingsOf 3416 participants who met inclusion criteria, 38.9% were male, and mean age +/- SD was 33.8 +/- 16.9 years. The age- and sex-adjusted prevalence of hypertension was 31.5% (95% confidence interval [CI] 30.2 to 32.8). The adjusted prevalence of hypertension was highest in the Central Region (34.3%; 95% CI 32.6 to 36.0), and it was comparable to that in the West and East Regions. However, compared with the Central Region, hypertension was significantly less prevalent in the North (22.0%; 95 CI 19.4 to 24.6) and West Nile Regions (24.1%; 95% CI 22.0 to 26.3). Adjustment for demographic characteristics (occupation, monthly income, and educational attainment) of participants did not account for the significantly lower prevalence of hypertension in the North and West Nile Regions. The prevalence of pre-hypertension was 38.8% (95% CI 37.7 to 39.8), and it was highly prevalent among young adults (21-40 years of age: 42.8%; 95% CI 41.2-44.5%) in all regions.ConclusionsHypertension is starkly prevalent in Uganda, and numerous more people, including young adults are at increased risk. The burden of hypertension is highest in the Central, Western, and Eastern regions of the country; demographic characteristics did not fully account for the disparate regional burden of hypertension. Future studies should explore the potential additional impact of epidemiological shifts, including diet and lifestyle changes, on the development of hypertension. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b181a6323e35a3f5cc1e91f4a53a2ce6Test https://doi.org/10.1371/journal.pone.0201001Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b181a6323e35a3f5cc1e91f4a53a2ce6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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