Joint data analysis in nutritional epidemiology:Identification of observational studies and minimal requirements
| العنوان: | Joint data analysis in nutritional epidemiology:Identification of observational studies and minimal requirements |
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| المؤلفون: | Rosario Lombardo, Luis Castaño, Janette Walton, Michèle Guillaume, Katharina Nimptsch, Jean Tafforeau, Christophe Matthys, Antonietta Robino, Heiner Boeing, Christina Kleiser, Marie Standl, Eha Nurk, Thorsten Heuer, Ute Nöthlings, Mariona Pinart, Chen Yang, Maria De Angelis, Paolo Gasparini, Jakob Linseisen, Marco Gobbetti, Jordi Merino, Jildau Bouwman, Luis Masana, Birgit Christiane Zyriax, Lars O. Dragsted, Nathalie De Cock, Tobias Pischon, Anne-Françoise Donneau, Raffaella Canali, Holger Schulz, Eberhard Windler, Elena Biagi, Eamon Laird, Giuditta Perozzi, Marta Stelmach-Mardas, Stephanie Jeran, Massimo D'Archivio, Gemma Rojo-Martínez, Carl Lachat, Janett Barbaresko |
| المساهمون: | Pinart, Mariona, Nimptsch, Katharina, Bouwman, Jildau, Dragsted, Lars O., Yang, Chen, De Cock, Nathalie, Lachat, Carl, Perozzi, Giuditta, Canali, Raffaella, Lombardo, Rosario, D'Archivio, Massimo, Guillaume, Michèle, Donneau, Anne-Françoise, Jeran, Stephanie, Linseisen, Jakob, Kleiser, Christina, Nöthlings, Ute, Barbaresko, Janett, Boeing, Heiner, Stelmach-Mardas, Marta, Heuer, Thorsten, Laird, Eamon, Walton, Janette, Gasparini, Paolo, Robino, Antonietta, Castaño, Lui, Rojo-Martínez, Gemma, Merino, Jordi, Masana, Lui, Standl, Marie, Schulz, Holger, Biagi, Elena, Nurk, Eha, Matthys, Christophe, Gobbetti, Marco, de Angelis, Maria, Windler, Eberhard, Zyriax, Birgit-Christiane, Tafforeau, Jean, Pischon, Tobias |
| المصدر: | Pinart, M, Nimptsch, K, Bouwman, J, Dragsted, L O, Yang, C, De Cock, N, Lachat, C, Perozzi, G, Canali, R, Lombardo, R, D'Archivio, M, Guillaume, M, Donneau, A-F, Jeran, S, Linseisen, J, Kleiser, C, Nöthlings, U, Barbaresko, J, Boeing, H, Stelmach-Mardas, M, Heuer, T, Laird, E, Walton, J, Gasparini, P, Robino, A, Castaño, L, Rojo-Martínez, G, Merino, J, Masana, L, Standl, M, Schulz, H, Biagi, E, Nurk, E, Matthys, C, Gobbetti, M, de Angelis, M, Windler, E, Zyriax, B-C, Tafforeau, J & Pischon, T 2018, ' Joint data analysis in nutritional epidemiology : Identification of observational studies and minimal requirements ', Journal of Nutrition, vol. 148, no. 2, pp. 285-297 . https://doi.org/10.1093/jn/nxx037Test JOURNAL OF NUTRITION Journal of Nutrition, 2, 148, 285-297 |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Agriculture and Food Sciences, 0301 basic medicine, Blood Glucose, INFORMATION, Cross-sectional study, Epidemiology, Health Status, Statistics as Topic, Medicine (miscellaneous), Longitudinal Studie, DETERMINANTS, GUIDELINES, PHENOTYPE, Health Statu, Cohort Studies, Faculty of Science, Insulin, Longitudinal Studies, Lipoprotein, Child, Nutritional phenotype, Nutrition and Dietetics, ASSOCIATION, Genomics, Europe, Nutritional Statu, Research proposal, Observational Studies as Topic, Data integration, Case-Control Studie, Raw data, INTEGRATION, Human, Cohort study, Adult, Lipoproteins, Data sharing, Metadata, Observational studies, Biomarkers, Case-Control Studies, Chronic Disease, Cross-Sectional Studies, Humans, Inflammation, Life Style, Metabolomics, Diet, Nutritional Status, Metabolomic, 03 medical and health sciences, AGE, Environmental health, ddc:610, Biology, Cross-Sectional Studie, 030109 nutrition & dietetics, Nutritional epidemiology, Biomarker, Observational studie, 030104 developmental biology, Cardiovascular and Metabolic Diseases, Genomic, FOOD-CONSUMPTION, Observational study, Cohort Studie |
| الوصف: | BACKGROUND: Joint data analysis from multiple nutrition studies may improve the ability to answer complex questions regarding the role of nutritional status and diet in health and disease. OBJECTIVE: The objective was to identify nutritional observational studies from partners participating in the European Nutritional Phenotype Assessment and Data Sharing Initiative (ENPADASI) Consortium, as well as minimal requirements for joint data analysis. METHODS: A predefined template containing information on study design, exposure measurements (dietary intake, alcohol and tobacco consumption, physical activity, sedentary behavior, anthropometric measures, and sociodemographic and health status), main health-related outcomes, and laboratory measurements (traditional and omics biomarkers) was developed and circulated to those European research groups participating in the ENPADASI under the strategic research area of "diet-related chronic diseases." Information about raw data disposition and metadata sharing was requested. A set of minimal requirements was abstracted from the gathered information. RESULTS: Studies (12 cohort, 12 cross-sectional, and 2 case-control) were identified. Two studies recruited children only and the rest recruited adults. All studies included dietary intake data. Twenty studies collected blood samples. Data on traditional biomarkers were available for 20 studies, of which 17 measured lipoproteins, glucose, and insulin and 13 measured inflammatory biomarkers. Metabolomics, proteomics, and genomics or transcriptomics data were available in 5, 3, and 12 studies, respectively. Although the study authors were willing to share metadata, most refused, were hesitant, or had legal or ethical issues related to sharing raw data. Forty-one descriptors of minimal requirements for the study data were identified to facilitate data integration. CONCLUSIONS: Combining study data sets will enable sufficiently powered, refined investigations to increase the knowledge and understanding of the relation between food, nutrition, and human health. Furthermore, the minimal requirements for study data may encourage more efficient secondary usage of existing data and provide sufficient information for researchers to draft future multicenter research proposals in nutrition. ispartof: The Journal of Nutrition vol:148 issue:2 pages:285-297 ispartof: location:United States status: published |
| وصف الملف: | application/pdf; Print |
| اللغة: | English |
| تدمد: | 0022-3166 1541-6100 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00bb688c812ef8f8bf67737446b639cTest https://curis.ku.dk/portal/da/publications/joint-data-analysis-in-nutritional-epidemiologyTest(66cff4d5-8a32-4802-a4e1-b5cc93cd6dd5).html |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b00bb688c812ef8f8bf67737446b639c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00223166 15416100 |
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