Idiopathic Polyneuropathy in Alaskan Malamutes
| العنوان: | Idiopathic Polyneuropathy in Alaskan Malamutes |
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| المؤلفون: | H. Steven Steinberg, Moore Mp, K. G. Braund, Rod S. Bagley, Steiss Je, Chuck T. Lowrie, Andy Shores |
| المصدر: | Journal of Veterinary Internal Medicine, Vol 11, Iss 4, Pp 243-249 (1997) |
| بيانات النشر: | Wiley, 1997. |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | Male, Myelinated nerve fiber, Schwann cell, Exercise intolerance, Breeding, Quadriplegia, Nerve Fibers, Myelinated, Dogs, Prevalence, medicine, Animals, Dog Diseases, Remyelination, Gait, Tetraplegia, lcsh:Veterinary medicine, General Veterinary, business.industry, Peroneal Nerve, Hyperesthesia, Anatomy, medicine.disease, Sciatic Nerve, Axons, Muscle atrophy, Paresis, Muscular Atrophy, medicine.anatomical_structure, Nerve Degeneration, Disease Progression, lcsh:SF600-1100, Female, Nervous System Diseases, Tibial Nerve, medicine.symptom, business, Polyneuropathy |
| الوصف: | Clinical and morphologic features of a progressive polyneuropathy in young mature Alaskan Malamutes are described. Clinical signs included progressive paraparesis, synchronous pelvic limb gait, exercise intolerance, hyperesthesia, hypore-flexia, muscle atrophy, and tetraplegia. Electromyographic testing revealed diffuse fibrillation potentials and positive sharp waves in limb muscles, especially in muscles below the elbow and stifle. Pathologic findings in skeletal muscles and peripheral nerves included neurogenic muscle atrophy, focal or diffuse loss of myelinated nerve fibers, myelinoaxonal necrosis, and variable demyelination or remyelination. Ultrastructural changes included axonal degeneration, presence of numerous Bungner bands, and denervated Schwann cell subunits. The nature and distribution of abnormal electrophysiologic and pathologic findings were suggestive of a distal sensorimotor polyneuropathy, which we have termed idiopathic polyneuropathy of Alaskan Malamutes to distinguish this condition from hereditary polyneuropathy of Norwegian Alaskan Malamutes, last described in 1982. |
| تدمد: | 1939-1676 0891-6640 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af83b2d7c363d7f1c54d9e3f7e946f14Test https://doi.org/10.1111/j.1939-1676.1997.tb00098.xTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....af83b2d7c363d7f1c54d9e3f7e946f14 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19391676 08916640 |
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