Assessment of corticospinal excitability after traumatic spinal cord injury using MEP recruitment curves: a preliminary TMS study
| العنوان: | Assessment of corticospinal excitability after traumatic spinal cord injury using MEP recruitment curves: a preliminary TMS study |
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| المؤلفون: | Stefan Golaszewski, Yvonne Höller, Eugen Trinka, Raffaele Nardone, Aljoscha Thomschewski, Francesco Brigo, AR Ellis, Arne C. Bathke |
| المصدر: | Spinal Cord. 53:534-538 |
| بيانات النشر: | Springer Science and Business Media LLC, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Traumatic spinal cord injury, medicine.medical_treatment, Pyramidal Tracts, Pilot Projects, Physical medicine and rehabilitation, medicine, Humans, Evoked potential, Spinal cord injury, Spinal Cord Injuries, Motor threshold, Motor cortical function, business.industry, Motor Cortex, Cervical Cord, General Medicine, Middle Aged, Evoked Potentials, Motor, medicine.disease, Functional recovery, Transcranial Magnetic Stimulation, Transcranial magnetic stimulation, medicine.anatomical_structure, Neurology, Female, Neurology (clinical), business, Neuroscience, Motor cortex |
| الوصف: | Transcranial magnetic stimulation study. To further investigate the corticospinal excitability changes after spinal cord injury (SCI), as assessed by means of transcranial magnetic stimulation (TMS). Merano (Italy) and Salzburg (Austria). We studied resting motor threshold (RMT), motor evoked potential (MEP) amplitude and recruitment curve in five subjects with good recovery after traumatic incomplete cervical SCI. RMT did not differ significantly between patients and controls, whereas the slope of MEP recruitment curve was significantly increased in the patients. This abnormal finding may represent an adaptive response after SCI. The impaired ability of the motor cortex to generate proper voluntary movement may be compensated by increasing spinal excitability. The easily performed measurement of MEP recruitment curve may provide a useful additional tool to improve the assessment and monitoring of motor cortical function in subjects with SCI. Increasing our knowledge of the corticospinal excitability changes in the functional recovery after SCI may also support the development of effective therapeutic strategies. |
| تدمد: | 1476-5624 1362-4393 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4707f17fb0486832592f207dd6294fTest https://doi.org/10.1038/sc.2015.12Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ad4707f17fb0486832592f207dd6294f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14765624 13624393 |
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