Outer retina dysfunction and choriocapillaris impairment in type 1 diabetes
| العنوان: | Outer retina dysfunction and choriocapillaris impairment in type 1 diabetes |
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| المؤلفون: | Simona Frontoni, Giuseppe Querques, Riccardo Sacconi, Fabiana Picconi, Eliana Costanzo, V. Parisi, Monica Varano, A Di Renzo, Enrico Borrelli, Mariacristina Parravano, Lucia Ziccardi |
| المساهمون: | Parravano, M., Ziccardi, L., Borrelli, E., Costanzo, E., Frontoni, S., Picconi, F., Parisi, V., Sacconi, R., Di Renzo, A., Varano, M., Querques, G. |
| المصدر: | Scientific Reports Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021) |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, genetic structures, chemistry.chemical_compound, Settore MED/13, 0302 clinical medicine, Medicine, Tomography, Multidisciplinary, Angiography, Diabetic retinopathy, Middle Aged, Reflectivity, Retinal diseases, Type 1 diabetes, medicine.anatomical_structure, Female, Perfusion, Tomography, Optical Coherence, Type 1, Adult, medicine.medical_specialty, Science, Article, Retina, Young Adult, 03 medical and health sciences, Ophthalmology, Diabetes Mellitus, Electroretinography, Humans, Response Amplitude, Aged, Diabetic Retinopathy, Choroid, business.industry, Retinal Vessels, Retinal, Optical coherence tomography angiography, medicine.disease, eye diseases, Cross-Sectional Studies, Diabetes Mellitus, Type 1, 030104 developmental biology, chemistry, Optical Coherence, Case-Control Studies, 030221 ophthalmology & optometry, sense organs, business |
| الوصف: | To study the outer retina morpho-functional characteristics and the choriocapillaris (CC) features in type 1 diabetic (T1D) patients, with and without signs of diabetic retinopathy (NPDR and NoDR). Twenty-five NPDR and 18 NoDR eyes were imaged by Optical Coherence Tomography Angiography. Ellipsoid zone (EZ) “normalized” reflectivity and CC perfusion density parameters, as flow deficits number (FDn), flow deficit average area (FDa) and flow deficit percentage (FD%), were analysed. Multifocal electroretinogram (mfERG) response amplitude densities (RADs) were measured. Mean EZ “normalized” reflectivity, CC FDn and FD% values, were similar (p > 0.05) in both groups, FDa was significant greater (p > 0.05) in NPDR compared with NoDR eyes. MfERG-RADs were similar in both groups. NPDR eyes showed a significant (p |
| تدمد: | 2045-2322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa9dfc9809800a3ebfc7901e0783715Test https://doi.org/10.1038/s41598-021-94580-zTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....aaa9dfc9809800a3ebfc7901e0783715 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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