Emotional working memory in patients with major depressive disorder
| العنوان: | Emotional working memory in patients with major depressive disorder |
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| المؤلفون: | Shengfu Lu, Mi Li, Lei Feng, Bingbing Fu, Ning Zhong, Ming Zhang, Bin Hu, Gang Wang, Xingwang Liu |
| المصدر: | Journal of International Medical Research, Vol 46 (2018) The Journal of International Medical Research |
| بيانات النشر: | SAGE Publishing, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Medicine (General), Emotions, Sternberg WM paradigm, emotion, Audiology, working memory (WM), Biochemistry, behavioral disciplines and activities, 050105 experimental psychology, 03 medical and health sciences, 0302 clinical medicine, R5-920, mental disorders, Reaction Time, Humans, Medicine, 0501 psychology and cognitive sciences, In patient, Depression (differential diagnoses), Demography, Depressive Disorder, Major, Depression, business.industry, Working memory, 05 social sciences, Biochemistry (medical), Significant difference, WM encoding, Research Reports, Cell Biology, General Medicine, medicine.disease, Memory, Short-Term, Major depressive disorder, Female, business, 030217 neurology & neurosurgery, WM retrieval |
| الوصف: | Objective This study was performed to examine the working memory (WM) encoding and retrieval abilities in patients with major depressive disorder (MDD) and determine whether a mood-congruent memory effect is present. Methods The modified Sternberg WM paradigm with positive, negative, and neutral emotional pictures was used to investigate the WM abilities of 26 patients with MDD and 26 healthy controls (HCs). Results No significant difference in picture WM was found between the MDD and HC groups; however, the accuracy of picture position WM was significantly lower and the response time was significantly longer in the MDD than HC group, regardless of the picture or position WM. Additionally, in the MDD group, the accuracy of negative picture/position WM was significantly higher than that of positive picture/position WM. Conclusions These results suggest that in patients with MDD, spatial WM impairment was more severe than object WM. In addition, these patients’ WM retrieval was impaired, resulting in a decrease in WM retrieval ability, which may be an important cause of the slow thought in patients with MDD. Moreover, patients with depression have a mood-congruent memory effect, which may be an important factor in the occurrence and maintenance of depression. |
| اللغة: | English |
| تدمد: | 1473-2300 0300-0605 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a92e2d9472b7072be9bf53b8b1813214Test https://doaj.org/article/ecc7d323f46a44d8a63246056f4dd529Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a92e2d9472b7072be9bf53b8b1813214 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14732300 03000605 |
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