Inverted internal limiting membrane flap technique in eyes with large idiopathic full-thickness macular hole: long-term functional and morphological outcomes
| العنوان: | Inverted internal limiting membrane flap technique in eyes with large idiopathic full-thickness macular hole: long-term functional and morphological outcomes |
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| المؤلفون: | Mathias Maier, Julia Sabina Friedrich, Nikolaus Feucht, Chris P. Lohmann, Nathalie Bleidißel, Julian Klaas |
| المصدر: | Graefe's Archive for Clinical and Experimental Ophthalmology |
| بيانات النشر: | Springer Berlin Heidelberg, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Visual acuity, genetic structures, Visual Acuity, Basement Membrane, Closure rate, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, Optical coherence tomography, Ophthalmology, Vitrectomy, medicine, Full-thickness macular hole, Inverted internal limiting membrane flap technique, Spectral-domain optical coherence tomography, Humans, External limiting membrane, Macular hole, Retrospective Studies, Large macular hole, medicine.diagnostic_test, business.industry, Internal limiting membrane, Retinal, Flap appearance, medicine.disease, Retinal Perforations, Sensory Systems, eye diseases, ddc, medicine.anatomical_structure, chemistry, 030221 ophthalmology & optometry, Retinal Disorders, sense organs, Macular hole index, medicine.symptom, business, 030217 neurology & neurosurgery, Tomography, Optical Coherence |
| الوصف: | Purpose To investigate morphological and functional outcomes of the inverted internal limiting membrane (I-ILM) flap technique in large (≥ 400 μm) idiopathic full-thickness macular holes (FTMH) over a follow-up period of 12 months. Methods In this retrospective study, 55 eyes of 54 consecutive patients were enrolled. Best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT, Heidelberg, Spectralis) were performed preoperatively as well as 1, 3, 6, 9, and 12 months postoperatively. Special focus was put on the reintegration of outer retinal layers and the different ILM flap appearances. Results FTMH closure rate was 100% (55/55). BCVA significantly improved over the follow-up period of 12 months from 0.98 ± 0.38 LogMAR preoperatively to 0.42 ± 0.33 LogMAR at 12 months postoperatively (p Conclusion Our study highlights the favorable morphological and functional outcomes of the I-ILM flap technique in the short as well as in the long term. While complete ELM restoration revealed to be an important factor for improvement in BCVA, the different postoperative ILM flap appearances seem not to be related to BCVA. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1435-702X 0721-832X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ef3cf426cd75142e3444c1d72e11abTest http://europepmc.org/articles/PMC8277619Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a8ef3cf426cd75142e3444c1d72e11ab |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1435702X 0721832X |
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