Assessment of factors that determine the mean absolute relative difference in flash glucose monitoring with reference to plasma glucose levels in Japanese subjects without diabetes
| العنوان: | Assessment of factors that determine the mean absolute relative difference in flash glucose monitoring with reference to plasma glucose levels in Japanese subjects without diabetes |
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| المؤلفون: | Shunichi Matsumoto, Tsugumichi Saito, Satoshi Yoshino, Ryota Uehara, Eijiro Yamada, Kazuhiko Horiguchi, Yasuyo Nakajima, Emi Ishida, Ryo Shibusawa, Shuichi Okada, Masanobu Yamada |
| المصدر: | Endocrine Journal. 67:537-544 |
| بيانات النشر: | Japan Endocrine Society, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Blood Glucose, Male, Endocrinology, Diabetes and Metabolism, Physiology, 030209 endocrinology & metabolism, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Insulin resistance, Japan, Diabetes mellitus, Linear regression, medicine, Humans, Fasting blood sugar, Oral glucose tolerance, Plasma glucose, business.industry, Continuous glucose monitoring, Blood Glucose Self-Monitoring, Glucose Tolerance Test, medicine.disease, 030220 oncology & carcinogenesis, Female, Insulin Resistance, business, Body mass index |
| الوصف: | The Abbott FreeStyle Libre flash glucose monitoring system (FGM) is a recently introduced, but widespread continuous glucose monitoring system. While its mean absolute relative difference (MARD) value indicating its accuracy is acceptable with reference to the self-monitoring of blood glucose (SMBG) levels, few reports have examined the MARD in sensor glucose values of FGM (FGM-SG) with reference to plasma glucose (PG) levels and the factors determining it. We performed oral glucose tolerance tests (OGTTs) in 25 Japanese subjects without diabetes. Parkes error grid analyses showed that FGM-SG with either SMBG or PG levels as a reference met International Organization for Standardization criteria. The MARD in FGM-SG with reference to SMBG levels was 10.9 ± 4.1% during OGTTs. Surprisingly, the MARD in FGM-SG with reference to PG levels was 20.3 ± 10.3% during OGTTs, revealing a discrepancy in the accuracy of FGM-SG compared with that of PG levels; moreover, the MARD showed negative correlations with fasting blood sugar level, homeostasis model assessment insulin resistance index, and body mass index (BMI). Multiple regression analyses revealed that BMI contributed the most to the MARD when FGM-SG and PG level were compared, as lean individuals have a greater MARD regardless of glucose levels. Inaccurate FGM data could potentially increase the risk of inappropriate treatment; consideration of such factors is critical to ensure reliable FGM values. |
| تدمد: | 1348-4540 0918-8959 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d234316f2f0a39f05a3337a0d1edc8Test https://doi.org/10.1507/endocrj.ej19-0488Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a5d234316f2f0a39f05a3337a0d1edc8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13484540 09188959 |
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