The CSF Accumulator: Its Role in the Central Nervous System and Implications for Advancing Hydrocephalus Shunt Technology
| العنوان: | The CSF Accumulator: Its Role in the Central Nervous System and Implications for Advancing Hydrocephalus Shunt Technology |
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| المؤلفون: | A M Liakos, G Magram |
| المصدر: | Pediatric Neurosurgery. 26:236-246 |
| بيانات النشر: | S. Karger AG, 1997. |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | Energy Transfer/physiology, Cerebrospinal fluid, Cerebrospinal Fluid Pressure, Homeostasis, Child, Cerebrospinal Fluid Shunts/adverse effects/instrumentation, Fluid Shifts, Cerebrospinal Fluid, Intracranial pressure, Cerebrospinal Fluid/*physiology, General Medicine, Spinal Canal/growth & development, Cerebrospinal Fluid Shunts, Hydrocephalus/cerebrospinal fluid/complications/surgery, medicine.anatomical_structure, Pulsatile Flow, Cardiology, Drainage, Shunt (electrical), Gravitation, Hydrocephalus, Adult, medicine.medical_specialty, Posture/physiology, Posture, Central nervous system, Prosthesis Design, Central nervous system disease, Pulsatile Flow/physiology, Internal medicine, medicine, Humans, Cerebrospinal Fluid Pressure/*physiology, Fluid Shifts/physiology, business.industry, Lumbosacral Region, Infant, medicine.disease, Homeostasis/*physiology, Surgery, Accumulator (energy), Drainage/adverse effects/instrumentation, Energy Transfer, Pediatrics, Perinatology and Child Health, Neurology (clinical), Shunt dependency, Prosthesis Design/standards, business, Spinal Canal |
| الوصف: | The 'cerebrospinal fluid (CSF) accumulator' plays an important physiological role in the healthy central nervous system as both a shock absorber and regulator of drainage. In the presence of hydrocephalus, this function is compromised by resistance to the flow of CSF. It is further compromised by the placement of a standard shunt which allows only for one-way directional diversion of the fluid. Complications associated with shunt dependency may be a direct consequence of both the condition, and a failure of existing systems to restore the normal accumulator function. This article reviews the pathophysiology of the 'CSF accumulator' as it relates to hydrocephalus and its management, and proposes a biomimetic shunt designed to restore the 'CSF accumulator' toward normal. It is hoped that such a device will support normalization of intracranial pressure and restore an appropriate level of CSF volume in the shunted patient. Pediatr Neurosurg |
| تدمد: | 1423-0305 1016-2291 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a392cbfbfc112c4858c4578d49df5392Test https://doi.org/10.1159/000121198Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a392cbfbfc112c4858c4578d49df5392 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14230305 10162291 |
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