Renal Insufficiency and Secondary Hyperparathyroidism in Elderly Patients
| العنوان: | Renal Insufficiency and Secondary Hyperparathyroidism in Elderly Patients |
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| المؤلفون: | A. C. Silver, J S Woodhead, R C Brown, G Turner, Gregory J. Seymour |
| المصدر: | Scopus-Elsevier |
| بيانات النشر: | SAGE Publications, 1991. |
| سنة النشر: | 1991 |
| مصطلحات موضوعية: | Male, 030213 general clinical medicine, medicine.medical_specialty, Kidney Glomerulus, Clinical Biochemistry, Population, Urology, Renal function, chemistry.chemical_element, 030209 endocrinology & metabolism, Calcium, 03 medical and health sciences, 0302 clinical medicine, Calcitriol, Internal medicine, medicine, Vitamin D and neurology, Humans, education, Aged, Calcifediol, Bone mineral, Kidney, Hyperparathyroidism, education.field_of_study, business.industry, General Medicine, medicine.disease, Hospitalization, Endocrinology, medicine.anatomical_structure, chemistry, Parathyroid Hormone, Female, Hyperparathyroidism, Secondary, Kidney Diseases, Secondary hyperparathyroidism, business, Glomerular Filtration Rate |
| الوصف: | Glomerular filtration rate (GFR) is frequently reduced in elderly people. However, the effect of this on mineral metabolism in this population has received little attention. GFR, serum intact parathyroid hormone (PTH) and vitamin D metabolites were measured in 37 patients admitted to hospital for various reasons. In 20 patients with GFR greater than 50 mL/min, an elevated serum intact PTH concentration (greater than 5.4 pmol/L) was found in two, while in 17 patients with GFR less than 50 mL/min PTH was elevated in 13. One of this group was hypercalcaemic and presumed to have primary hyperparathyrodism. Adjusted calcium was normal in all other patients. Two patients had a low serum 25-hydroxyvitamin D concentration (less than 9 nmol/L) suggesting vitamin D insufficiency while a further five had a reduced 1,25-dihydroxyvitamin D concentration, four of these having a GFR less than 50 mL/min. We conclude that hyperparathyrodism is common in hospitalized elderly patients, particularly in those with mild to moderate renal insufficiency. This may contribute to bone mineral loss in such patients. |
| تدمد: | 1758-1001 0004-5632 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f68436ab7841e57b9b5ef7c0d72fe12Test https://doi.org/10.1177/000456329102800401Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....9f68436ab7841e57b9b5ef7c0d72fe12 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17581001 00045632 |
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