Opioid Use After Colorectal Resection: Identifying Preoperative Risk Factors for Postoperative Use

التفاصيل البيبلوغرافية
العنوان: Opioid Use After Colorectal Resection: Identifying Preoperative Risk Factors for Postoperative Use
المؤلفون: Brittany E. Levy, Jennifer T. Castle, Laura M. Ebbitt, Caleb Kennon, Erin McAtee, Daniel L. Davenport, B. Mark Evers, Avinash Bhakta
المصدر: The Journal of surgical research. 283
سنة النشر: 2022
مصطلحات موضوعية: Surgery
الوصف: Appropriate prescribing practices are imperative to ensure adequate pain control, without excess opioid dispensing across colorectal patients.National Surgical Quality Improvement Program, Kentucky All Scheduled Prescription Electronic Reporting, and patient charts were queried to complete a retrospective study of elective colorectal resections, performed by a fellowship-trained colorectal surgeon, from January 2013 to December 2020. Opioid use at 14 d and 30 d posthospital discharge converted into morphine milligram equivalents (MMEs) were analyzed and compared across preadmission and inpatient factors.One thousand four hundred twenty seven colorectal surgeries including 56.1% (N = 800) partial colectomy, 24.1% (N = 344) low anterior resection, 8.3% (N = 119) abdominoperineal resection, 8.4% (N = 121) sub/total colectomy, and 3.0% (N = 43) total proctocolectomy. Abdominoperineal resection and sub/total colectomy patients had higher 30-day postdischarge MMEs (P 0.001, P = 0.041). An operative approach did not affect postdischarge MMEs (P = 0.440). Trans abdominal plane blocks do not predict postdischarge MMEs (0.616). Epidural usage provides a 15% increase in postdischarge MMEs (P = 0.020). Age (P 0.001), smoking (P 0.001), chronic obstructive pulmonary disease (P = 0.006,0.001), dyspnea (P = 0.001,0.001), albumin3.5 (P = 0.085, 0.010), disseminated cancer (P = 0.018, 0.001), and preadmission MMEs (P 0.001) predict elevated 14-day and 30-day postdischarge MMEs.We conclude that perioperative analgesic procedures, as enhanced recovery pathway suggests, are neither predictive nor protective of postoperative discharge MMEs in colorectal surgery. Provider should account for preoperative risk factors when prescribing discharge opioid medications. Furthermore, providers should identify appropriate adjunct procedures to improve discharge opioid prescription stewardship.
تدمد: 1095-8673
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5a1432814b7768a30981fa7d7835c4Test
https://pubmed.ncbi.nlm.nih.gov/36423479Test
حقوق: CLOSED
رقم الانضمام: edsair.doi.dedup.....9e5a1432814b7768a30981fa7d7835c4
قاعدة البيانات: OpenAIRE