Involvement of Apoptosis in Host-Parasite Interactions in the Zebra Mussel
| العنوان: | Involvement of Apoptosis in Host-Parasite Interactions in the Zebra Mussel |
|---|---|
| المؤلفون: | Laetitia Minguez, Nelly Brulé, Simon Devin, Bénédicte Sohm, Laure Giamberini |
| المساهمون: | Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Terre et Environnement de Lorraine (OTELo), Institut national des sciences de l'Univers (INSU - CNRS)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | PLoS ONE PLoS ONE, Vol 8, Iss 6, p e65822 (2013) PLoS ONE, Public Library of Science, 2013, 8 (6), ⟨10.1371/journal.pone.0065822⟩ |
| بيانات النشر: | Public Library of Science, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Male, Programmed cell death, Anatomy and Physiology, Histology, Science, Apoptosis, 010501 environmental sciences, Biology, 01 natural sciences, Microbiology, Dreissena, Host-Parasite Interactions, 03 medical and health sciences, Heat shock protein, Bucephalus polymorphus, Molecular Cell Biology, Parasite hosting, Animals, HSP70 Heat-Shock Proteins, 030304 developmental biology, 0105 earth and related environmental sciences, Cellular Stress Responses, 0303 health sciences, Multidisciplinary, TUNEL assay, Cell Death, Intracellular parasite, Parasite Physiology, biology.organism_classification, 3. Good health, Cell biology, Hsp70, Host-Pathogen Interaction, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, MESH: HEAT-SHOCK PROTEINS, PROGRAMMED CELL-DEATH, DREISSENA-POLYMORPHA, ANAPLASMA-PHAGOCYTOPHILUM, EHRLICHIA-CHAFFEENSIS, CRASSOSTREA-VIRGINICA, BACTERIAL PATHOGENS, DIGESTIVE GLAND, IMMUNE-SYSTEM, OSTREA-EDULIS, [SDE]Environmental Sciences, Medicine, Parasitology, Female, Physiological Processes, Zoology, Research Article |
| الوصف: | International audience; The question of whether cell death by apoptosis plays a biological function during infection is key to understanding host-parasite interactions. We investigated the involvement of apoptosis in several host-parasite systems, using zebra mussels Dreissena polymorpha as test organisms and their micro-and macroparasites. As a stress response associated with parasitism, heat shock proteins (Hsp) can be induced. In this protein family, Hsp70 are known to be apoptosis inhibitors. Mussels were diagnosed for their respective infections by standard histological methods; apoptosis was detected using the TUNEL methods on paraffin sections and Hsp70 by immunohistochemistry on cryosections. Circulating hemocytes were the main cells observed in apoptosis whereas infected tissues displayed no or few apoptotic cells. Parasitism by intracellular bacteria Rickettsiales-like and the trematode Bucephalus polymorphus were associated with the inhibition of apoptosis whereas ciliates Ophryoglena spp. or the trematode Phyllodistomum folium did not involve significant differences in apoptosis. Even if some parasites were able to modulate apoptosis in zebra mussels, we did not see evidence of any involvement of Hsp70 on this mechanism. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d10253427b65470fc86a33a3263a37fTest http://europepmc.org/articles/PMC3681881Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9d10253427b65470fc86a33a3263a37f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
|---|