Sex Differences in Autoimmune Multimorbidity in Type 1 Diabetes Mellitus and the Risk of Cardiovascular and Renal Disease: A Longitudinal Study in the United States, 2001–2017
| العنوان: | Sex Differences in Autoimmune Multimorbidity in Type 1 Diabetes Mellitus and the Risk of Cardiovascular and Renal Disease: A Longitudinal Study in the United States, 2001–2017 |
|---|---|
| المؤلفون: | Joyce M. Lee, Catherine Kim, Melissa Y. Wei, Mary A.M. Rogers |
| المصدر: | J Womens Health (Larchmt) |
| بيانات النشر: | Mary Ann Liebert Inc, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, Longitudinal study, medicine.medical_specialty, Adolescent, Myocardial Infarction, 030209 endocrinology & metabolism, Disease, medicine.disease_cause, Autoimmune Diseases, Autoimmunity, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Prevalence, Humans, Medicine, Multimorbidity, Longitudinal Studies, Renal Insufficiency, 030212 general & internal medicine, Child, Aged, Aged, 80 and over, Sex Characteristics, Type 1 diabetes, business.industry, Original Articles, General Medicine, Middle Aged, medicine.disease, United States, Stroke, Diabetes Mellitus, Type 1, Child, Preschool, Female, business |
| الوصف: | Background: Autoimmune diseases are usually more prevalent in women. The risks of cardiovascular and renal disease in those with multiple autoimmune diseases have not been fully described. Materials and Methods: Using a national database from a large health insurer in the United States (years 2001–2017) containing ∼75 million members, we calculated age- and sex-specific co-prevalence of 12 autoimmune disorders for individuals with type 1 diabetes. We then evaluated whether concomitant autoimmune diseases were associated with renal failure, ischemic stroke, and myocardial infarction. Results: Of the 179,248 people diagnosed with type 1 diabetes, 1 in 4 had a concomitant autoimmune disease (27.03%; 95% confidence interval [CI] = 26.83%–27.24%), with hypothyroidism, rheumatoid arthritis, and celiac disease being the most common. The prevalence of autoimmune disease was 1.9 times greater in female than male patients (p |
| تدمد: | 1931-843X 1540-9996 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c915a3727413eee99222703a1e42096Test https://doi.org/10.1089/jwh.2019.7935Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9c915a3727413eee99222703a1e42096 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1931843X 15409996 |
|---|