THE RELATIONSHIP OF COEXISTING EXTRANIDAL ANEURYSMS TO INTRACRANIAL HEMORRHAGE IN PATIENTS HARBORING BRAIN ARTERIOVENOUS MALFORMATIONS
| العنوان: | THE RELATIONSHIP OF COEXISTING EXTRANIDAL ANEURYSMS TO INTRACRANIAL HEMORRHAGE IN PATIENTS HARBORING BRAIN ARTERIOVENOUS MALFORMATIONS |
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| المؤلفون: | Christopher F. Dowd, Michael T. Lawton, Alexander X. Halim, Vineeta Singh, William L. Young, Eui Jong Kim, John Bennett |
| المصدر: | Neurosurgery. 54:1349-1358 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2004. |
| سنة النشر: | 2004 |
| مصطلحات موضوعية: | Adult, Intracranial Arteriovenous Malformations, Male, medicine.medical_specialty, Subarachnoid hemorrhage, Adolescent, Aneurysm, Ruptured, Aneurysm, Risk Factors, medicine.artery, medicine, Humans, cardiovascular diseases, Child, Aged, Retrospective Studies, Aged, 80 and over, medicine.diagnostic_test, business.industry, Vascular disease, Intracranial Aneurysm, Magnetic resonance imaging, Arteriovenous malformation, Retrospective cohort study, Odds ratio, Middle Aged, medicine.disease, nervous system diseases, Surgery, Radiography, Child, Preschool, Female, Neurology (clinical), Radiology, business, Intracranial Hemorrhages, Circle of Willis |
| الوصف: | OBJECTIVE: We hypothesized that coexisting extranidal arterial aneurysms (EAs) would be associated with an increased risk of incident intracranial hemorrhage (ICH) from brain arteriovenous malformation (BAVM) rupture. METHODS: To determine the presence of EAs and compare the sources and locations of ICH, we retrospectively reviewed the computed tomographic, magnetic resonance imaging, and angiographic studies of patients who presented between 1990 and 1999. EAs were defined as saccular luminal dilations of the parent feeding vessels that were proximally flow-related (i.e., at the circle of Willis), distally flow-related (i.e., distal to the circle of Willis), and unrelated (i.e., in circulation distant from the BAVM). RESULTS: Of 314 BAVM patients, 138 (44%) presented with ICH. In the ICH group, 22 patients (16%) had aneurysmal ICH, 100 (72%) had BAVM ICH, and 16 (12%) had ICH from an indeterminate source. There were 61 patients with 1 or more EAs (29 patients with 42 flow-related proximal aneurysms, 39 patients with 48 flow-related distal aneurysms, and 10 patients with 20 unrelated aneurysms). Multivariate regression analysis revealed that ICH patients were more likely than non-ICH patients to have a coexisting EA (35 versus 13%; odds ratio = 3.9; 95% confidence interval, 2.1-7.5; P < 0.001), but this effect was not present when only BAVM-related ICH was considered (odds ratio = 0,3; 95% confidence interval, 0.1-1.0; P = 0.052). Other independent predictors of ICH included small AVM size ( |
| تدمد: | 1524-4040 0148-396X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b943e9666002fae8a57669fb113b07bTest https://doi.org/10.1227/01.neu.0000124483.73001.12Test |
| رقم الانضمام: | edsair.doi.dedup.....9b943e9666002fae8a57669fb113b07b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15244040 0148396X |
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