Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota
| العنوان: | Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota |
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| المؤلفون: | Sebastian Napp, Laia Sobrevia, Virginia Aragon, Lourdes Migura-Garcia, Carlos Neila-Ibáñez, Sergio López-Soria, Simon Tibble, Florencia Correa-Fiz, Blanca Martinez |
| المساهمون: | Producció Animal, Sanitat Animal |
| المصدر: | Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020) Scientific Reports Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona IRTA Pubpro. Open Digital Archive Institut de Recerca i Tecnologia Agroalimentàries (IRTA) |
| بيانات النشر: | Nature Portfolio, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, Streptococcus suis, Swine, Polymerase Chain Reaction, Feces, chemistry.chemical_compound, fluids and secretions, Anti-Infective Agents, Pregnancy, 2. Zero hunger, Multidisciplinary, Antimicrobials, Microbiota, Fatty Acids, Agriculture, Antimicrobial, 3. Good health, Parity, Treatment Outcome, Medicine, Female, Lysozyme, medicine.drug, Ruminococcaceae, DNA, Bacterial, Animal feed, Offspring, Science, 030106 microbiology, Microbial communities, Weaning, Biology, Article, Microbiology, 03 medical and health sciences, Streptococcal Infections, medicine, Animals, Amoxicillin, biology.organism_classification, Animal Feed, Nasal Mucosa, 030104 developmental biology, chemistry, Dietary Supplements, Food Additives, Muramidase |
| الوصف: | Medicated feed is a common strategy to control the occurrence of Streptococcus suis disease in swine production, but feed additives may constitute an alternative to metaphylaxis. In a farm with post-weaning S. suis disease, the following additives were tested: lysozyme (Lys), medium chain fatty acids plus lysozyme (FA + Lys), FA plus a natural anti-inflammatory (FA + antiinf) and amoxicillin (Amox). During the course of the study, FA + antiinf and Amox groups showed lower prevalence of clinical signs compatible with S. suis disease than the rest of the groups. Piglets from the FA + antiinf group showed high diversity and richness in their nasal and faecal microbiota. Diet supplements did not have major effects on the faecal microbiota, where the genus Mitsuokella was the only differentially present in the FA + Lys group. In the nasal microbiota, piglets from FA + antiinf presented higher differential abundance of a sequence variant from Ruminococcaceae and lower abundance of an unclassified genus from Weeksellaceae. In general, we detected more significant changes in the nasal than in the feacal microbiota, and found that parity of the dams affected the microbiota composition of their offspring, with piglets born to gilts exhibiting lower richness and diversity. Our results suggest that additives could be useful to control post-weaning disease when removing antimicrobials in farms. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2045-2322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adce5eee9c11c504091b88b4b49642bTest https://doaj.org/article/2ad2ad94d62743639a465a285bfe0612Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9adce5eee9c11c504091b88b4b49642b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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