Maternal metabolic response to dietary treatment for impaired glucose tolerance and gestational diabetes mellitus
| العنوان: | Maternal metabolic response to dietary treatment for impaired glucose tolerance and gestational diabetes mellitus |
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| المؤلفون: | Thomas P. Smith, Fionnuala M. McAuliffe, Mensud Hatunic, Lorraine Brennan, Sinead Curran, Karen L. Lindsay, Michael E. Foley, Mary Coffey, Maria A. Kennelly |
| المصدر: | Irish Journal of Medical Science (1971 -). 187:701-708 |
| بيانات النشر: | Springer Science and Business Media LLC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Blood Glucose, medicine.medical_specialty, endocrine system diseases, Diet therapy, medicine.medical_treatment, 030209 endocrinology & metabolism, Overweight, Impaired glucose tolerance, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Pregnancy, Internal medicine, Glucose Intolerance, medicine, Humans, Glycemic, 030219 obstetrics & reproductive medicine, business.industry, Insulin, nutritional and metabolic diseases, General Medicine, Glucose Tolerance Test, medicine.disease, Gestational diabetes, Diabetes, Gestational, Female, Nutrition Therapy, medicine.symptom, business, Body mass index |
| الوصف: | Dietary advice is a standard component of treatment for pregnant women with impaired glucose tolerance (IGT) and gestational diabetes (GDM), yet few studies report glycemic profiles in response to dietary therapies and the optimal dietary approach remains uncertain. To assess changes in maternal glycemic profile and pregnancy outcomes among women with diet-controlled IGT and GDM. Pregnant women who had one or more elevated values on a 3-h oral glucose tolerance test were enrolled. All participants received dietary advice and glucose monitoring as part of routine clinical care. Fasting and 1-h post-prandial blood samples, collected prior to initiation of clinical treatment and repeated 4–6 weeks later, were analyzed for glucose, insulin, and C-peptide. Homeostasis model assessment of insulin resistance (HOMA-IR) was calculated. Women who required pharmacological therapy for glucose control were excluded from analyses. Participants (N = 93) were of moderately older age (mean 33 years), with a high rate of overweight/obesity (mean body mass index (BMI) = 28.65 kg/m2), and were diagnosed late in gestation (mean 29 weeks). Fasting (mean ± SD 4.82 ± 0.53 to 4.60 ± 0.42 mmol/l; p |
| تدمد: | 1863-4362 0021-1265 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b3a8de984607fac8b211b14ddfe19bTest https://doi.org/10.1007/s11845-018-1744-yTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....97b3a8de984607fac8b211b14ddfe19b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18634362 00211265 |
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