Predictors of Long-Term Diabetes Remission After Metabolic Surgery
| العنوان: | Predictors of Long-Term Diabetes Remission After Metabolic Surgery |
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| المؤلفون: | Kong-Han Ser, Ming Hsien Lee, Jung-Chien Chen, Shu-Chun Chen, Keong Chong, Wei-Jei Lee, Yi-Chih Lee |
| المصدر: | Journal of Gastrointestinal Surgery. 19:1015-1021 |
| بيانات النشر: | Springer Science and Business Media LLC, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Adult, Blood Glucose, Male, medicine.medical_specialty, Time Factors, endocrine system diseases, Bariatric Surgery, Type 2 diabetes, Gastroenterology, Body Mass Index, chemistry.chemical_compound, Insulin resistance, Weight loss, Internal medicine, Diabetes mellitus, Weight Loss, medicine, Humans, Obesity, Postoperative Period, Glycated Hemoglobin, Univariate analysis, ABCD² score, business.industry, Remission Induction, nutritional and metabolic diseases, medicine.disease, Surgery, Treatment Outcome, Diabetes Mellitus, Type 2, chemistry, Female, Glycated hemoglobin, medicine.symptom, business, Body mass index, Follow-Up Studies |
| الوصف: | Bariatric/metabolic surgery has been proposed for the treatment of inadequately controlled type 2 diabetes mellitus (T2DM) in obese patients. However, prediction on successful long-term remission of T2DM after metabolic surgery has not been clearly studied. Our objectives were to evaluate rates of long-term remission of T2DM after metabolic surgery and determine the independent predictors of remission. Outcomes of 157 patients who underwent metabolic surgery between 2006 and 2009 and who had complete 5-year follow-up data were assessed. Prolonged complete remission was defined as glycated hemoglobin (HbA1c) less than 6 % without diabetes medication up to 5 years. Predictors of prolonged remission studies included patient characteristics such as glucose level, HbA1c, body weight, waist circumference, blood pressure, total cholesterol, LDL, triglyceride, uric acid, AST, alanine transaminase (ALT), albumin, insulin, C-peptide, iron, calcium, complete blood cell count, the ABCD score (a multidimensional grading system composed of age, body mass index (BMI), C-peptide levels, and duration of T2DM), and postoperative weight loss. At 5 years after surgery, the weight loss was 27.1 % and the mean BMI decreased from 39.8 to 28.8 kg/m2. The mean HbA1c decreased from 8.3 to 6.0 %. A significant number of patients had improvement in their glycemic control, including 97 (71.3 %) patients who had complete remission (HbA1c |
| تدمد: | 1873-4626 1091-255X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95bd5ec8a415c885504c2765c7743f71Test https://doi.org/10.1007/s11605-015-2808-1Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....95bd5ec8a415c885504c2765c7743f71 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18734626 1091255X |
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