التفاصيل البيبلوغرافية
العنوان:
Evaluation of HIV-specific T-cell responses in HIV-infected older patients with controlled viremia on long-term antiretroviral therapy
المؤلفون:
Anne M. Wertheimer , Stephen A. Klotz , Maria Love , Nicole E. Behrens , Nafees Ahmad
المصدر:
PLoS ONE
بيانات النشر:
Public Library of Science, 2020.
سنة النشر:
2020
مصطلحات موضوعية:
Male , 0301 basic medicine , RNA viruses , Viral Diseases , T-Lymphocytes , CD4-CD8 Ratio , HIV Infections , Pathology and Laboratory Medicine , Granzymes , White Blood Cells , 0302 clinical medicine , Medical Conditions , Immunodeficiency Viruses , Animal Cells , Cellular types , Medicine and Health Sciences , Medicine , Public and Occupational Health , Aged, 80 and over , Multidisciplinary , T Cells , Immune cells , virus diseases , Middle Aged , Viral Load , Vaccination and Immunization , medicine.anatomical_structure , Infectious Diseases , Anti-Retroviral Agents , Medical Microbiology , Viral Pathogens , Viruses , Female , Tumor necrosis factor alpha , medicine.symptom , Pathogens , Viral load , Research Article , Adult , Cell biology , Blood cells , Science , T cell , Immunology , Cell Enumeration Techniques , Antiretroviral Therapy , Inflammation , Viremia , Cytotoxic T cells , Research and Analysis Methods , Microbiology , Interferon-gamma , 03 medical and health sciences , Immune system , Antiviral Therapy , Lysosomal-Associated Membrane Protein 1 , Virology , Retroviruses , Humans , Microbial Pathogens , Aged , Biology and life sciences , Tumor Necrosis Factor-alpha , business.industry , Lentivirus , Organisms , HIV , medicine.disease , 030104 developmental biology , Age Groups , People and Places , Population Groupings , Preventive Medicine , business , CD8 , Viral Transmission and Infection , 030215 immunology
الوصف:
HIV-infected older individuals may have a diminished immune response because of exhaustion/immune aging of T-cells. Therefore, we have investigated HIV-specific CD4 and CD8 T-cell responses in 100 HIV-infected patients (HIV+) who have aged on long-term antiretroviral therapy (ART) and achieved controlled viremia (mostly undetectable viral load; 92 patients with
اللغة:
English
تدمد:
1932-6203
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952acd788a8fc1bd6bb2ca7a5b798899Test http://europepmc.org/articles/PMC7498024Test
حقوق:
OPEN
رقم الانضمام:
edsair.doi.dedup.....952acd788a8fc1bd6bb2ca7a5b798899
قاعدة البيانات:
OpenAIRE
