التفاصيل البيبلوغرافية
| العنوان: |
Antimicrobial Susceptibilities of Brucella Isolates from Various Clinical Speciemens |
| المؤلفون: |
Cenk Aypak, Selçuk Kiliç, Hanifi Körkoca, Aytekin Çikman, Mustafa Berktaş, Yasemin Bayram, Mehmet Parlak |
| المصدر: |
International Journal of Medical Sciences |
| بيانات النشر: |
Ivyspring International Publisher, 2011. |
| سنة النشر: |
2011 |
| مصطلحات موضوعية: |
Turkey, Minocycline, Microbial Sensitivity Tests, Tigecycline, Brucella, Antimicrobial susceptibility, Brucellosis, Microbiology, Trimethoprim, Sulfamethoxazole Drug Combination, Brucella melitensis, Humans, Medicine, Doxycycline, biology, business.industry, E-test, General Medicine, Antimicrobial, medicine.disease, biology.organism_classification, Anti-Bacterial Agents, Streptomycin, Rifampin, business, Research Paper, medicine.drug |
| الوصف: |
Purpose: Brucellosis is a worldwide zoonotic disease and still constitutes a major public health problem. In the study we claimed to identify Brucella species from clinical samples of patients with active brucellosis from Van region of Eastern Anatolia and to determine in vitro antimicrobial susceptibilities of these strains to commonly used anti-Brucella agents and a possible new alternative tigecycline. Materials and Methods: A total of 56 Brucella isolates were enrolled the study and the identification of the isolates were based on conventional methods. In vitro activities of an-timicrobials were evaluated by the E test method. Results: All isolates were identified as B. melitensis. MIC90 values of doxycycline, strepto-mycin, rifampin, trimethoprim-sulfamethoxazole and tigecycline were 0.064 mg/L, 1 mg/L, 2 mg/L, 0.125 mg/L and 0.094 mg/L, respectively. Tigecycline had low MIC50 and MIC90 values against all B. melitensis strains; the highest MIC observed was 0.25 ?g/mL. Conclusion: Our data suggest that tigecycline can be a therapeutic alternative option for the treatment of brucellosis. © Ivyspring International Publisher. |
| تدمد: |
1449-1907 |
| الوصول الحر: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f9055207bf47152bf70e980561aa2cTest
https://doi.org/10.7150/ijms.8.198Test |
| حقوق: |
OPEN |
| رقم الانضمام: |
edsair.doi.dedup.....93f9055207bf47152bf70e980561aa2c |
| قاعدة البيانات: |
OpenAIRE |
