Preclinical evaluation of the simultaneous inhibition of MCL-1 and BCL-2 with the combination of S63845 and venetoclax in multiple myeloma
| العنوان: | Preclinical evaluation of the simultaneous inhibition of MCL-1 and BCL-2 with the combination of S63845 and venetoclax in multiple myeloma |
|---|---|
| المؤلفون: | Pedro Mogollón, Lorena González-Méndez, Andrea Díaz-Tejedor, Montserrat Martín-Sánchez, Esperanza M Algarín, Enrique M. Ocio, Ensar Halilovic, Norma C. Gutiérrez, Sébastien Banquet, Maria-Victoria Mateos, Laura San-Segundo, Teresa Paíno, Mercedes Garayoa, Susana Hernández-García, Heiko Maacke, Alix Derreal, Laurence Kraus-Berthier, Luis A. Corchete, Ioana Kloos, Marie Schoumacher |
| المساهمون: | Instituto de Salud Carlos III, Junta de Castilla y León, European Commission, Universidad de Cantabria |
| المصدر: | Digital.CSIC. Repositorio Institucional del CSIC instname Haematologica . 2020 Mar;105(3):e116-e120 UCrea Repositorio Abierto de la Universidad de Cantabria Universidad de Cantabria (UC) |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Oncology, medicine.medical_specialty, Thiophenes, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Bridged Bicyclo Compounds, Internal medicine, Cell Line, Tumor, medicine, Humans, Online Only Articles, Multiple myeloma, Sulfonamides, Venetoclax, business.industry, Hematology, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, Myeloid Cell Leukemia Sequence 1 Protein, Pyrimidines, chemistry, Proto-Oncogene Proteins c-bcl-2, business, Multiple Myeloma, 030215 immunology |
| الوصف: | This work was supported by the Spanish ISCIII-FIS and FEDER Funds (PI 15/00067 and PI 15/02156) and the Regional Health Council of Castilla y León (GRS 1604/A/17). EMA was supported by a grant from the Regional Education Council of Castilla y León co-financed by the European Social Fund. |
| تدمد: | 1592-8721 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d44ea51fc5752fed67abba7f22e3a9Test https://pubmed.ncbi.nlm.nih.gov/31320555Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....93d44ea51fc5752fed67abba7f22e3a9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15928721 |
|---|