Reduction of periprosthetic Staphylococcus aureus infection by preoperative screening and decolonization of nasal carriers undergoing total knee arthroplasty
| العنوان: | Reduction of periprosthetic Staphylococcus aureus infection by preoperative screening and decolonization of nasal carriers undergoing total knee arthroplasty |
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| المؤلفون: | Alba Romero, Xavier Pelfort, Amparo García, Montserrat Brugués, Anna Marrón, Sergi Gil |
| المصدر: | Acta Orthopaedica et Traumatologica Turcica Acta Orthopaedica et Traumatologica Turcica, Vol 53, Iss 6, Pp 426-431 (2019) |
| بيانات النشر: | Turkish Association of Orthopaedics and Traumatology, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Staphylococcus aureus, Total knee arthroplasty, Periprosthetic, Decolonization protocol, S. aureus, medicine.disease_cause, TKR infection, 03 medical and health sciences, 0302 clinical medicine, lcsh:Orthopedic surgery, Preoperative Care, medicine, Humans, Surgical Wound Infection, Orthopedics and Sports Medicine, Arthroplasty, Replacement, Knee, Aged, Retrospective Studies, 030222 orthopedics, business.industry, Incidence (epidemiology), Incidence, Preoperative screening, Chlorhexidine, Retrospective cohort study, 030229 sport sciences, General Medicine, Staphylococcal Infections, TKA infection, Surgery, Anti-Bacterial Agents, lcsh:RD701-811, Mupirocin, Nasal Swab, Spain, Carrier State, Female, Screening protocol, business, medicine.drug, Research Article |
| الوصف: | Objective: The aim of this study was to evaluate whether the establishment of a preoperative screening and decolonization protocol for Staphylococcus aureus carriers undergoing total knee arthroplasty (TKA) could decrease the incidence of periprosthetic joint infection (PJI) caused by this microorganism. Methods: We conducted a retrospective study comparing a control group comprising 400 patients (134 men, and 266 women; mean age: 72.2 ± 6.8 years) who went through surgery between January 2009 and December 2013, with a second intervention group of 403 patients (125 men, and 278 women; mean age: 72.4 ± 6.9 years) in which the protocol of screening and decolonization of S. aureus nasal carriers was applied between January 2014 and December 2016. During this latter period patients were preoperatively screened and, if positive, treated with mupirocin nasal ointment and chlorhexidine soap, for 5 days prior to surgery. Results: In the control group, 17 of 400 patients (4.2%) had a SSI, 8 (2%) of them caused by S. aureus and 9 (2.2%) by other microorganisms. In the intervention group 20.6% of patients had a positive S. aureus nasal swab and were treated according to the protocol. 5 of 403 patients (1.2%) in this group had a SSI, 1 (0.2%) due to S. aureus and 4 (1%) to other microorganisms. When comparing surgical-site infection (SSI) rates between the two groups, we found a statistically significant reduction in both global SSI (p = 0.009) and specifically S. aureus SSI (p = 0.02), in the intervention group. No decolonized S. aureus nasal carrier presented a SSI. Discussion: In patients undergoing TKA a preoperative screening and decolonization protocol for S. aureus nasal carriers, using mupirocin nasal ointment and chlorhexidine soap, is an effective measure to reduce the rate of SSI caused by this microorganism. Level of Evidence: Level III; Therapeutic Study. Keywords: S. aureus, TKA infection, Screening protocol, Decolonization protocol, TKR infection |
| اللغة: | English |
| تدمد: | 2589-1294 1017-995X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d2cd0b9da29ee26897038fb569b862Test http://europepmc.org/articles/PMC6938997Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....91d2cd0b9da29ee26897038fb569b862 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25891294 1017995X |
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