Abnormal gait pattern emerges during curved trajectories in high-functioning Parkinsonian patients walking in line at normal speed
| العنوان: | Abnormal gait pattern emerges during curved trajectories in high-functioning Parkinsonian patients walking in line at normal speed |
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| المؤلفون: | Marco Godi, Ilaria Arcolin, Andrea Giordano, Marco Schieppati, Marica Giardini, Antonio Nardone, Anna Maria Turcato |
| المصدر: | PLoS ONE PLoS ONE, Vol 13, Iss 5, p e0197264 (2018) |
| بيانات النشر: | Public Library of Science, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, 030506 rehabilitation, Kinematics, Physiology, lcsh:Medicine, Walking, 0302 clinical medicine, Postural Balance, Medicine and Health Sciences, Medicine, lcsh:Science, Musculoskeletal System, Gait, Cognitive Impairment, Multidisciplinary, Movement Disorders, Cognitive Neurology, Physics, Classical Mechanics, Neurodegenerative Diseases, Parkinson Disease, Biomechanical Phenomena, Neurology, Physical Sciences, Legs, Female, Anatomy, 0305 other medical science, Cadence, Gait Analysis, Research Article, medicine.medical_specialty, Patients, Cognitive Neuroscience, STRIDE, 03 medical and health sciences, Physical medicine and rehabilitation, Humans, Gait Disorders, Neurologic, Balance (ability), Aged, Balance and Falls, business.industry, Biological Locomotion, lcsh:R, Limbs (Anatomy), Biology and Life Sciences, Preferred walking speed, Health Care, Geriatrics, Gait analysis, Cognitive Science, lcsh:Q, business, human activities, 030217 neurology & neurosurgery, Neuroscience |
| الوصف: | Background Several patients with Parkinson´s disease (PD) can walk normally along straight trajectories, and impairment in their stride length and cadence may not be easily discernible. Do obvious abnormalities occur in these high-functioning patients when more challenging trajectories are travelled, such as circular paths, which normally implicate a graded modulation in the duration of the interlimb gait cycle phases? Methods We compared a cohort of well-treated mildly to moderately affected PD patients to a group of age-matched healthy subjects (HS), by deliberately including HS spontaneously walking at the same speed of the patients with PD. All participants performed, in random order: linear and circular walking (clockwise and counter-clockwise) at self-selected speed. By means of pressure-sensitive insoles, we recorded walking speed, cadence, duration of single support, double support, swing phase, and stride time. Stride length-cadence relationships were built for linear and curved walking. Stride-to-stride variability of temporal gait parameters was also estimated. Results Walking speed, cadence or stride length were not different between PD and HS during linear walking. Speed, cadence and stride length diminished during curved walking in both groups, stride length more in PD than HS. In PD compared to HS, the stride length-cadence relationship was altered during curved walking. Duration of the double-support phase was also increased during curved walking, as was variability of the single support, swing phase and double support phase. Conclusion The spatio-temporal gait pattern and variability are significantly modified in well-treated, high-functioning patients with PD walking along circular trajectories, even when they exhibit no changes in speed in straight-line walking. The increased variability of the gait phases during curved walking is an identifying characteristic of PD. We discuss our findings in term of interplay between control of balance and of locomotor progression: the former is challenged by curved trajectories even in high-functioning patients, while the latter may not be critically affected. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a1aacbde66d92e048b92a5fb3c37b6Test http://europepmc.org/articles/PMC5947908Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....91a1aacbde66d92e048b92a5fb3c37b6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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