Effect of Obstructive Sleep Apnea Treatment on Lipids in Obese Children

التفاصيل البيبلوغرافية
العنوان: Effect of Obstructive Sleep Apnea Treatment on Lipids in Obese Children
المؤلفون: Zarlasht Amini, Suresh Kotagal, Robin M. Lloyd, Swetha Sriram, Seema Kumar, Christine M. Lohse
المصدر: Children; Volume 4; Issue 6; Pages: 44
Children
بيانات النشر: Multidisciplinary Digital Publishing Institute, 2017.
سنة النشر: 2017
مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, Article, Childhood obesity, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, 030225 pediatrics, Internal medicine, medicine, Continuous positive airway pressure, obstructive sleep apnea, business.industry, Cholesterol, dyslipidemia, cholesterol, medicine.disease, Obesity, nervous system diseases, respiratory tract diseases, Obstructive sleep apnea, Endocrinology, Apnea–hypopnea index, chemistry, childhood obesity, continuous positive airway pressure, Pediatrics, Perinatology and Child Health, business, Body mass index, 030217 neurology & neurosurgery, Dyslipidemia
الوصف: Obesity in children is associated with several co-morbidities including dyslipidemia. Obstructive sleep apnea (OSA) is commonly seen in obese children. In adults, diagnosis of OSA independent of obesity is associated with cardiometabolic risk factors including dyslipidemia. There is limited data on the impact of treatment of OSA on lipids in children. The objective of the study was to examine the impact of treatment of OSA on lipids in 24 obese children. Methods: Seventeen children were treated with continuous positive airway pressure (CPAP) and five underwent adenotonsillectomy. Mean apnea hypopnea index prior to treatment was 13.0 + 12.1 and mean body mass index (BMI) was 38.0 + 10.6 kg/m2. Results: Treatment of OSA was associated with improvement in total cholesterol (mean change = −11 mg/dL, p < 0.001), and low-density lipoprotein cholesterol (mean change = –8.8 mg/dL, p = 0.021). Conclusion: Obese children should be routinely screened for OSA, as treatment of OSA favorably influences lipids and therefore decreases their cardiovascular risk.
وصف الملف: application/pdf
اللغة: English
تدمد: 2227-9067
DOI: 10.3390/children4060044
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc9999138789aaa0345c1f827047435Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....8dc9999138789aaa0345c1f827047435
قاعدة البيانات: OpenAIRE
الوصف
تدمد:22279067
DOI:10.3390/children4060044