DERMATOLOGIC LESIONS IN ASYMPTOMATIC BLOOD DONORS SEROPOSITIVE FOR HUMAN T CELL LYMPHOTROPIC VIRUS TYPE-1
| العنوان: | DERMATOLOGIC LESIONS IN ASYMPTOMATIC BLOOD DONORS SEROPOSITIVE FOR HUMAN T CELL LYMPHOTROPIC VIRUS TYPE-1 |
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| المؤلفون: | Fernando Augusto Proietti, José Roberto Lambertucci, Anna Barbara de Freitas Carneiro Proietti, Denise Utsch Gonçalves, Marina Lobato Martins, Antônio Carlos Martins Guedes |
| المصدر: | The American Journal of Tropical Medicine and Hygiene. 68:562-565 |
| بيانات النشر: | American Society of Tropical Medicine and Hygiene, 2003. |
| سنة النشر: | 2003 |
| مصطلحات موضوعية: | Adult, Male, Pathology, medicine.medical_specialty, Blood Donors, Polymerase Chain Reaction, Skin Diseases, Asymptomatic, Myelopathy, Virology, Seborrheic dermatitis, Tropical spastic paraparesis, Dermatomycoses, Humans, Medicine, Human T cell lymphotropic virus type 1, Skin, Human T-lymphotropic virus 1, business.industry, Ichthyosis, Middle Aged, medicine.disease, HTLV-I Infections, Dermatology, Dermatitis, Seborrheic, HTLV-I Antibodies, Infectious Diseases, DNA, Viral, Population study, Female, Parasitology, Viral disease, medicine.symptom, business, Asymptomatic carrier |
| الوصف: | Dermatologic manifestations are quite common in patients with adult T cell leukemia/lymphoma and myelopathy/tropical spastic paraparesis associated with infection with human T cell lymphotropic virus type-1 (HTLV-1). In this study, we evaluated the dermatologic lesions of eligible blood donors in the state of Minas Gerais in Brazil who were seropositive but asymptomatic for infection with HTLV-1. The study population was composed of 128 HTLV-1-seropositive individuals and 108 seronegative controls. All individuals underwent a dermatologic evaluation. Biopsy specimens were obtained from abnormal and normal skin samples of seropositive individuals in an attempt to detect HTLV-1 in tissue samples by a polymerase chain reaction. Dermatologic alterations were observed more frequently in the seropositive group (adjusted odds ratio [OR] = 8.77, 95% confidence interval [CI] = 4.11-18.71). The most common skin diseases were dermatophytoses (adjusted OR = 3.32, 95% CI = 1.50-7.35), seborrheic dermatitis (OR = 3.53, 95% CI = 0.67-24.66), and acquired ichthyosis (P = 0.001). Virus was detected more frequently in abnormal skin samples. Dermatologic lesions probably related to HTLV-1 infection were diagnosed in eligible blood donors who were infected with this virus, who were previously considered to be asymptomatic carriers of HTLV-1. |
| تدمد: | 1476-1645 0002-9637 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adce883d4134cdc0d047072209e1225Test https://doi.org/10.4269/ajtmh.2003.68.562Test |
| رقم الانضمام: | edsair.doi.dedup.....8adce883d4134cdc0d047072209e1225 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14761645 00029637 |
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