Effects of Selenium and Vitamin E on Enzymatic, Biochemical, and Immunological Biomarkers in Galleria mellonella L
| العنوان: | Effects of Selenium and Vitamin E on Enzymatic, Biochemical, and Immunological Biomarkers in Galleria mellonella L |
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| المؤلفون: | Emre Gulsu, Tamer Kayis, Mustafa Coskun, Emel Alp |
| المصدر: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020) |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0106 biological sciences, 0301 basic medicine, Hemocytes, Antioxidant, medicine.medical_treatment, lcsh:Medicine, chemistry.chemical_element, medicine.disease_cause, 01 natural sciences, Article, Superoxide dismutase, Selenium, 03 medical and health sciences, chemistry.chemical_compound, Animal physiology, medicine, Animals, Vitamin E, Micronutrients, Food science, lcsh:Science, Multidisciplinary, biology, lcsh:R, Micronutrient, Malondialdehyde, Diet, Lepidoptera, Oxidative Stress, 010602 entomology, 030104 developmental biology, chemistry, Catalase, biology.protein, lcsh:Q, Entomology, Oxidative stress |
| الوصف: | To understand the effects of micronutrients have particular biological functions that are involved mainly in the antioxidant system, which has essential implications for the development of diseases, this study investigated how vitamin E, selenium, and their combination affect lipid, protein, carbohydrate, and malondialdehyde (MDA) content; antioxidant enzyme (catalase [CAT], superoxide dismutase [SOD], glutathione-S-transferase [GST]) activity; and the total hemocyte count (THC) in larvae of Galleria mellonella L. fed different diets. Diet 1 (100 µg of selenium) significantly decreased carbohydrate and lipid content. Diets 2 (100 µg of vitamin E), 3 (100 µg of selenium and vitamin E each), and 5 (Tween 80) did not significantly affect protein and carbohydrate content. Diet 2 significantly increased the lipid content compared to diet 4 (control). Diet 1 increased CAT, SOD, and GST activity and MDA content (highest at 27.64 nmol/mg protein). Diet 2 significantly decreased SOD activity and MDA content compared to other diets. Diet 1 significantly decreased the THC compared to other diets. These results suggested that selenium changes oxidative stress parameters, energy reserves, and THC in G. mellonella. These changes could be a physiological adaptation against selenium-induced oxidative stress. Vitamin E could play a protective role in selenium toxicity. |
| تدمد: | 2045-2322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4a1a02c97081105b71aa3790a3a323Test https://doi.org/10.1038/s41598-020-67072-9Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8a4a1a02c97081105b71aa3790a3a323 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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