Use of tumor markers to distinguish endometriosis-related ovarian neoplasms from ovarian endometrioma
| العنوان: | Use of tumor markers to distinguish endometriosis-related ovarian neoplasms from ovarian endometrioma |
|---|---|
| المؤلفون: | Yohei Tsunoda, Takehiko Fukami, Hiroki Shinmura, Toshiyuki Takeshita, Koichi Yoneyama, Eika Harigane, Takashi Matsushima |
| المصدر: | International Journal of Gynecological Cancer |
| بيانات النشر: | BMJ, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, medicine.medical_specialty, endocrine system diseases, Endometriosis, Gastroenterology, Diagnosis, Differential, Young Adult, chemistry.chemical_compound, Antigen, ovarian cysts, Internal medicine, Lactate dehydrogenase, Biomarkers, Tumor, medicine, Humans, Single institution, Original Research, Aged, Aged, 80 and over, Ovarian Neoplasms, Ovarian Endometrioma, Mural Nodule, Tumor size, business.industry, Obstetrics and Gynecology, Middle Aged, medicine.disease, Oncology, chemistry, Case-Control Studies, Serum ca125, Female, business |
| الوصف: | ObjectiveOnly few studies have focused on tumor markers used in the preoperative diagnosis of endometriosis-related ovarian neoplasms, and previous studies have only assessed serum CA125 levels. This study investigated the significance of preoperative tumor markers and clinical characteristics in distinguishing endometriosis-related ovarian neoplasms from ovarian endometrioma.MethodsA case-control study was conducted on 283 women who were diagnosed with confirmed pathology with endometriosis-related ovarian neoplasms (n=21) and ovarian endometrioma (n=262) at a single institution from April 2008 to April 2018. The serum CA125, CA19–9, carcinoembryogenic antigen (CEA), sialyl Lewis-x antigen (SLX), and lactate dehydrogenase (LDH) levels, age, tumor size, and the presence of mural nodule of the patients were analyzed.ResultsPatients with endometriosis-related ovarian neoplasms were more likely to be older (48 (range, 26–81) vs 39 (range, 22–68) years, PConclusionsThe assessment of serum CA19–9, CEA, SLX, and LDH levels may be a useful tool in the preoperative evaluation to differentiate between endometriosis-related ovarian neoplasms and ovarian endometrioma. |
| تدمد: | 1525-1438 1048-891X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ddbe48f5f145aac3c7255fb56b9f66Test https://doi.org/10.1136/ijgc-2020-001210Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....89ddbe48f5f145aac3c7255fb56b9f66 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15251438 1048891X |
|---|