An integrative review of standardized clinical evaluation tool utilization in anticholinergic drug trials for neurogenic lower urinary tract dysfunction
| العنوان: | An integrative review of standardized clinical evaluation tool utilization in anticholinergic drug trials for neurogenic lower urinary tract dysfunction |
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| المؤلفون: | Darren Lazare, Brian Tsang, Mark Nigro, Lynn Stothers, Andrew J. Macnab |
| المصدر: | Spinal Cord |
| بيانات النشر: | Springer Science and Business Media LLC, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | medicine.medical_specialty, Population, 030232 urology & nephrology, Cholinergic Antagonists, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, medicine, Humans, Urinary Bladder, Neurogenic, Intensive care medicine, Oxybutynin, education, Spinal Cord Injuries, Randomized Controlled Trials as Topic, education.field_of_study, Solifenacin, Trospium chloride, business.industry, General Medicine, Clinical trial, Neuromuscular Agents, Neurology, 030220 oncology & carcinogenesis, Physical therapy, Original Article, Spine injury, Neurology (clinical), Tolterodine, business, medicine.drug |
| الوصف: | Study design: To review prospective and randomized trials studying anticholinergic therapy for neurogenic bladder in SCI to identify whether trials included standardized clinical evaluation tools and reporting measures now recognized to enhance clinical trial data. Methods: A systematic search via EMBASE, MEDLINE, CENTRAL, CINAHL (Cumulative Index to Nursing and Allied Health Literature), HTA (Health Technology Assessment), CMR (Comprehensive Microbial Resource), HAPI (Health and Psychosocial Instruments) and PsycINFO using the key term spinal cord injury crossed with oxybutynin, tolterodine, darifenacin, solifenacin, fesoterodine, trospium chloride, propiverine, propantheline and anticholinergic(s) for 1946–2015 inclusive. We then collated whether standardized clinical tools, measures and descriptors were used within each study identified: American Spine Injury Association (ASIA) impairment scale; symptom scores validated in SCI; technical methodology for urodynamics/video urodynamics; urinary diaries; and standardized urologic terminology. Results: A total of 1225 entries with 610 unique articles were identified, 14 randomized and 16 prospective studies. In 6/30 the population comprised SCI patients with neurogenic bladder alone; the remainder included mixed neurogenic etiologies. Classification using the ASIA impairment scale was used in |
| تدمد: | 1476-5624 1362-4393 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a79730d3c0827ffc27547832bf6ab1Test https://doi.org/10.1038/sc.2016.63Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....87a79730d3c0827ffc27547832bf6ab1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14765624 13624393 |
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