Estimation of HIV-1 incidence among five focal populations in Dehong, Yunnan: a hard hit area along a major drug trafficking route
| العنوان: | Estimation of HIV-1 incidence among five focal populations in Dehong, Yunnan: a hard hit area along a major drug trafficking route |
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| المؤلفون: | Song Duan, Yujiang Jia, Lifeng Xiang, Yan Jiang, Sten H. Vermund, Sheng Shen, H Jiang, Minjie Wang, Yuecheng Yang, Lin Lu, Marc Bulterys, Fei Tian, Yao Xiao, Manhong Jia |
| المصدر: | BMC Public Health BMC Public Health, Vol 10, Iss 1, p 180 (2010) |
| بيانات النشر: | BioMed Central, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, China, Population, Prevalence, HIV Infections, 030312 virology, 03 medical and health sciences, 0302 clinical medicine, Catchment Area, Health, HIV Seroprevalence, Pregnancy, Environmental health, Surveys and Questionnaires, Epidemiology, Research article, medicine, Humans, 030212 general & internal medicine, Marriage, education, Psychiatry, Spouses, Substance Abuse, Intravenous, Sex work, Estimation, 0303 health sciences, education.field_of_study, business.industry, lcsh:Public aspects of medicine, Incidence (epidemiology), Public health, Incidence, 1. No poverty, Public Health, Environmental and Occupational Health, virus diseases, AIDS Serodiagnosis, lcsh:RA1-1270, Sex Work, 3. Good health, Cross-Sectional Studies, Sexual Partners, Population Surveillance, HIV-1, Female, Biostatistics, business |
| الوصف: | Background Since 1989 when the first 146 HIV positives in China were identified, Dehong Prefecture had been one of the areas hardest-hit by HIV in China. The local and national governments have put substantial financial resources into tackling the HIV epidemic in Dehong from 2004. The objective of this study was to track dynamic changes in HIV-1 prevalence and incidence among five focal populations in Dehong and to assess the impact of HIV prevention and control efforts. Methods Consecutive cross-sectional surveys conducted in five focal populations between 2004 and 2008. Specimens seropositive for HIV were tested with the BED IgG capture enzyme immunoassay to identify recent seroconversions (median, 155 days) using normalized optical density of 0.8 and adjustments. Results From 2004 to 2008, estimated annual HIV incidence among injecting drug users (IDUs) decreased significantly [from 15.0% (95% CI = 11.4%-18.5%) in 2004 to 4.3% (95% CI = 2.4%-6.2%) in 2008; trend test P < 0.0001]. The incidence among other focal populations, such as HIV discordant couples (varying from 5.5% to 4.7%), female sex workers (varying from 1.4% to 1.3%), pregnant women (0.1%), and pre-marital couples (0.2 to 0.1%) remained stable. Overall, the proportion of recent HIV-1 infections was higher among females than males (P < 0.0001). Conclusions The HIV epidemic in Dehong continued to expand during a five-year period but at a slowing rate among IDUs, and HIV incidence remains high among IDUs and discordant couples. Intensive prevention measures should target sub-groups at highest risk to further slow the epidemic and control the migration of HIV to other areas of China, and multivariate analysis is needed to explore which measures are more effective for different populations. |
| اللغة: | English |
| تدمد: | 1471-2458 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8753e9ce34ef34a434aec7565906e1adTest http://europepmc.org/articles/PMC2858119Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8753e9ce34ef34a434aec7565906e1ad |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14712458 |
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