Investigation of maternal and cord blood erythropoietin and copeptin levels in low-risk term deliveries complicated by meconium-stained amniotic fluid
| العنوان: | Investigation of maternal and cord blood erythropoietin and copeptin levels in low-risk term deliveries complicated by meconium-stained amniotic fluid |
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| المؤلفون: | Necati Hancerliogullari, Özlem Moraloğlu, Nuri Danisman, Bergen Laleli, Hakan Timur, Hasan Ali Inal, Aytekin Tokmak, Selen Taflan |
| المصدر: | The Journal of Maternal-Fetal & Neonatal Medicine. 30:665-669 |
| بيانات النشر: | Informa UK Limited, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Adult, Meconium, medicine.medical_specialty, Amniotic fluid, Term Birth, Statistics, Nonparametric, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Copeptin, Pregnancy, Risk Factors, medicine, Humans, 030212 general & internal medicine, Erythropoietin, Meconium stained amniotic fluid, 030219 obstetrics & reproductive medicine, Obstetrics, business.industry, Glycopeptides, Infant, Newborn, Obstetrics and Gynecology, Gestational age, Hydrogen-Ion Concentration, Amniotic Fluid, Fetal Blood, medicine.disease, Pregnancy Complications, Cross-Sectional Studies, Case-Control Studies, Cord blood, Pediatrics, Perinatology and Child Health, Female, business, Biomarkers, medicine.drug |
| الوصف: | To compare maternal, cord blood erythropoietin (EPO), and copeptin levels in low-risk term deliveries which are complicated by meconium-stained amniotic fluid (MSAF) to those with clear amniotic fluid. Also, to evaluate the relations between these markers and cord blood pH values.Low-risk term pregnant women with MSAF at an active phase of labor were defined as the study group (n = 39). Pregnant women with clear amniotic fluid were selected for the control group (n = 41). The two groups were matched for age, body mass index and gestational age. Maternal, cord blood EPO and copeptin levels with cord blood pH values were also measured.Maternal, cord blood EPO, and copeptin levels of study and control groups were 42.6 ± 9.0 versus 40.7 ± 9.2, 134.2 (20.5-834.6) versus 38.4 (10.3-114.2), 4.9 (0.1-31.1) versus 4.0 (3.1-28.4), and 4.7 (2.6-25.5) versus 3.6 (2.0-23.2), respectively. The differences were statistically significant for cord blood EPO, maternal and cord blood copeptin levels (p 0.001, p = 0.004, p 0.001, respectively). The study group had a statistically and significantly lower cord blood pH values (7.25 ± 0.05 versus 7.34 ± 0.04, p 0.001). Moreover, cord blood EPO and maternal and cord blood copeptin levels were inversely correlated with cord blood pH values in the study group (p 0.001, p = 0.005, and p = 0.009, respectively).We suggest that higher cord blood EPO and maternal and cord blood copeptin levels may be an indicator of fetal acidosis in low-risk term deliveries complicated by MSAF. |
| تدمد: | 1476-4954 1476-7058 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8617dae9ca3c2fd87845b42089aa3e77Test https://doi.org/10.1080/14767058.2016.1182973Test |
| رقم الانضمام: | edsair.doi.dedup.....8617dae9ca3c2fd87845b42089aa3e77 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14764954 14767058 |
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