A rare case of tuberculosis-induced hypercalcemia
| العنوان: | A rare case of tuberculosis-induced hypercalcemia |
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| المؤلفون: | Damien Gruson, Patrick Durez, Diane Maisin, Xavier Theunssens, Catherine Fillée, Loris Wauthier |
| المصدر: | Biochemia Medica Volume 30 Issue 3 |
| بيانات النشر: | Croatian Society of Medical Biochemistry and Laboratory Medicine, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Vitamin, musculoskeletal diseases, calcitriol, medicine.medical_specialty, Tuberculosis, Calcitriol, Clinical Biochemistry, Parathyroid hormone, hypercalcemia, tuberculosis, rheumatoid polyarthritis, 030209 endocrinology & metabolism, Case Report, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Rare case, medicine, Vitamin D and neurology, 030212 general & internal medicine, business.industry, Biochemistry (medical), medicine.disease, chemistry, Rheumatoid arthritis, Right ankle, business, hormones, hormone substitutes, and hormone antagonists, medicine.drug |
| الوصف: | Laboratory investigations of hypercalcemia involve testing of various biochemical parameters such as parathyroid hormone (PTH), 25-(OH) Vitamin D (25-(OH) VitD), 1,25-(OH)2 Vitamin D3 (calcitriol) and PTH related peptide (PTHrp). We herein present an atypical case of severe hypercalcemia in a patient with rheumatoid arthritis who has been treated for years by various biological disease-modifying antirheumatic drugs (DMARDs) and suddenly presented with general state alteration, oedema and ulceration of her right ankle. We illustrate how tuberculosis (TB) can cause high calcitriol concentration and subsequently lead to potentially severe hypercalcemia. Moreover, we highlight the importance of TB testing and follow-up in patients treated with biological DMARDs. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1846-7482 1330-0962 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817bc0f021e1c12fece5f71ae16fd4f5Test http://europepmc.org/articles/PMC7394250Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....817bc0f021e1c12fece5f71ae16fd4f5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18467482 13300962 |
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