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Efficacy of nebivolol-valsartan single-pill combination in obese and nonobese patients with hypertension

التفاصيل البيبلوغرافية
العنوان: Efficacy of nebivolol-valsartan single-pill combination in obese and nonobese patients with hypertension
المؤلفون: Madhuja Mallick, William G. Ferguson, Mehul D. Patel, David B. Bharucha, Christian W. Mende, Thomas D. Giles
المصدر: Journal of Clinical Hypertension (Greenwich, Conn.)
بيانات النشر: Wiley, 2017.
سنة النشر: 2017
مصطلحات موضوعية: Male, obesity, Angiotensin receptor, Endocrinology, Diabetes and Metabolism, Blood Pressure, 030204 cardiovascular system & hematology, Biomarkers, Pharmacological, Body Mass Index, Nebivolol, chemistry.chemical_compound, 0302 clinical medicine, Heart Rate, Risk Factors, Medicine, 030212 general & internal medicine, Aldosterone, Blood Pressure Monitoring, Ambulatory, Middle Aged, Treatment Outcome, Valsartan, Adrenergic beta-1 Receptor Agonists, Drug Therapy, Combination, Female, Cardiology and Cardiovascular Medicine, Glomerular Filtration Rate, medicine.drug, Adult, medicine.medical_specialty, hypertension, Ambulatory blood pressure, Urology, Renal function, Therapetics, Placebo, valsartan, single‐pill combination, 03 medical and health sciences, Internal medicine, Internal Medicine, Humans, Antihypertensive Agents, Original Paper, business.industry, Endocrinology, Blood pressure, chemistry, business, Angiotensin II Type 1 Receptor Blockers
الوصف: Antihypertensive efficacy of single‐pill combinations (SPCs) consisting of a β1‐selective adrenergic blocker with vasodilatory properties via β3‐agonism (nebivolol) and an angiotensin II receptor blocker (valsartan) was demonstrated in an 8‐week phase 3 trial (NCT01508026). In this post hoc analysis, seated blood pressure, heart rate, 24‐hour ambulatory blood pressure monitoring, plasma aldosterone, estimated glomerular filtration rate, and safety measures were assessed in obese (body mass index >32 kg/m2; n=1823) and nonobese (body mass index
تدمد: 1524-6175
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815e021962bd296e5f11295077b241c0Test
https://doi.org/10.1111/jch.12965Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....815e021962bd296e5f11295077b241c0
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15246175