Superoxide dismutase 2 as a marker to differentiate tuberculous pleural effusions from malignant pleural effusions
| العنوان: | Superoxide dismutase 2 as a marker to differentiate tuberculous pleural effusions from malignant pleural effusions |
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| المؤلفون: | Mao-Shui Wang, Zhiqiang Zhang, Xin-Feng Wang |
| المصدر: | Clinics, Volume: 69, Issue: 12, Pages: 799-803, Published: 2014 Clinics, Vol 69, Iss 12, Pp 799-803 (2014) Clinics; v. 69 n. 12 (2014); 799-803 Clinics; Vol. 69 Núm. 12 (2014); 799-803 Clinics; Vol. 69 No. 12 (2014); 799-803 Clinics Universidade de São Paulo (USP) instacron:USP |
| بيانات النشر: | Faculdade de Medicina / USP, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Male, Pathology, Pleural effusion, Biopsy, Likelihood ratios in diagnostic testing, Malignant pleural effusion, Interferon gamma, Aged, 80 and over, lcsh:R5-920, medicine.diagnostic_test, biology, Tuberculosis, Pleural, General Medicine, Middle Aged, Clinical Science, respiratory system, Superoxide Dismutase 2, Biomarker (medicine), Female, Tumor necrosis factor alpha, lcsh:Medicine (General), medicine.drug, Adult, medicine.medical_specialty, Tuberculous Pleural Effusion, Adolescent, Enzyme-Linked Immunosorbent Assay, Statistics, Nonparametric, Diagnosis, Differential, Superoxide dismutase, Interferon-gamma, Young Adult, medicine, Humans, Aged, Retrospective Studies, Superoxide Dismutase, Tumor Necrosis Factor-alpha, business.industry, Malignant Pleural Effusion, Biomarker, Clinical Enzyme Tests, medicine.disease, Pleural Effusion, Malignant, respiratory tract diseases, Pleural Effusion, ROC Curve, biology.protein, Reactive Oxygen Species, business, Biomarkers |
| الوصف: | OBJECTIVES: Our previous study demonstrated that superoxide dismutase levels were higher in tuberculous pleural effusions than in malignant pleural effusions, but that this difference could not be used to discriminate between the two. The objective of the present study was to investigate the levels of superoxide dismutase 2 in pleural effusions and to evaluate the diagnostic significance of pleural effusion superoxide dismutase 2. METHODS: Superoxide dismutase 2 concentrations were determined in pleural effusions from 54 patients with tuberculous pleural effusion and 33 with malignant pleural effusion using an enzyme-linked immunosorbent assay (ELISA) kit. Pleural effusion interferon gamma and tumor necrosis factor alpha levels were also analyzed by ELISA. The Mann-Whitney U test was used to evaluate the significance of differences. Associations between superoxide dismutase 2 concentrations and sex, age and smoking habits were assessed using Spearman's or Pearson's correlation coefficient analysis. Receiver operator characteristic analysis was performed to evaluate the value of superoxide dismutase 2 levels in the discrimination of tuberculous pleural effusion from malignant pleural effusion. RESULTS: Superoxide dismutase 2 levels were significantly higher in patients with tuberculous pleural effusion compared with those with malignant pleural effusion (p |
| وصف الملف: | text/html; application/pdf |
| اللغة: | English |
| تدمد: | 1980-5322 1807-5932 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80dbfc54578e743944a58c23415545cfTest http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014001200799&lng=en&tlng=enTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....80dbfc54578e743944a58c23415545cf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19805322 18075932 |
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