Seroprevalence of human T-lymphotropic virus HTLV and its associated factors in donors of a blood bank of Medellín-Colombia, 2014-2018
| العنوان: | Seroprevalence of human T-lymphotropic virus HTLV and its associated factors in donors of a blood bank of Medellín-Colombia, 2014-2018 |
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| المؤلفون: | Jennifer Florez-Duque, Juan C. Zapata, Olga Victoria Calle-González, Jaiberth Antonio Cardona-Arias, Carolina Vélez-Quintero |
| المصدر: | PLoS ONE, Vol 14, Iss 8, p e0221060 (2019) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, Hemovigilance, Physiology, Cross-sectional study, Blood Donors, Human T-lymphotropic virus, Biochemistry, Geographical locations, 0302 clinical medicine, Seroepidemiologic Studies, Immune Physiology, Medicine and Health Sciences, Medicine, Enzyme-Linked Immunoassays, Geographic Areas, Human T-lymphotropic virus 1, education.field_of_study, Immune System Proteins, Multidisciplinary, Geography, biology, Human T-lymphotropic virus 2, Middle Aged, Infectious Diseases, Blood Banks, Female, Research Article, Urban Areas, Adult, Adolescent, Science, Immunology, 030231 tropical medicine, Population, Colombia, Opportunistic Infections, Research and Analysis Methods, Antibodies, 03 medical and health sciences, Chi-square test, Humans, Seroprevalence, Immunoassays, education, Aged, business.industry, Biology and Life Sciences, Proteins, Odds ratio, South America, biology.organism_classification, HTLV-I Infections, Health Care, Cross-Sectional Studies, 030104 developmental biology, Health Care Facilities, Age Groups, HTLV-II Infections, Immunologic Techniques, Earth Sciences, Population Groupings, People and places, business, Demography, Blood sampling |
| الوصف: | BackgroundResearch on HTLV in Colombia is limited; despite being an endemic country there are few studies on the magnitude of this infection. The aim of this study was to determine the seroprevalence of HTLV I/II and its associated factors in donors to a blood bank of Medellín Colombia, 2014-2018.MethodsThis is a cross-sectional study of 52,159 donors with a secondary information source. Seroprevalence of HTLV I/II was determined with its confidence interval and the population characteristics were described by frequency and summary measures. To explore the associated factors, Pearson's Chi square test, Mann-Whitney U test, crude odds ratios were used and they were adjusted by logistic regression in SPSS 25.0.Results88% of the population lived in the metropolitan area, 68.5% belonged to the University. 76.2% were altruistic donors (unpaid donors who did not donate to a specific patient). 24.5% were repetitive (paid) donors. 75% of the donors were under 41 years old. The seroprevalence of HTLV I/II was 0.176% (95% CI = 0.139% -0.213%), being statistically lower in repetitive donors and men.ConclusionThe seroprevalence of HTLV I/II infection in the studied blood bank is lower than that reported in other blood banks at the departmental and national levels. In Medellín, it was associated with the frequency of donation and gender, which is useful information for the hemovigilance programs of the city. |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e426ee1d44076917ca5648d395f8fb3Test https://doi.org/10.1371/journal.pone.0221060Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7e426ee1d44076917ca5648d395f8fb3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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