Preference of inhalants over pills/injections among pulmonary tuberculosis patients in Western India: A cross-sectional study
| العنوان: | Preference of inhalants over pills/injections among pulmonary tuberculosis patients in Western India: A cross-sectional study |
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| المؤلفون: | Kristin K. Sznajder, Rajendra Patil, Bushra Shaikh, Ahuja Nirmal |
| المصدر: | Journal of Clinical Tuberculosis and Other Mycobacterial Diseases Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 23, Iss, Pp 100234-(2021) |
| بيانات النشر: | Elsevier, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0301 basic medicine, Microbiology (medical), Pulmonary and Respiratory Medicine, Intoxicative inhalant, medicine.medical_specialty, Tuberculosis, Cross-sectional study, 030106 microbiology, Population, Infectious and parasitic diseases, RC109-216, Drug resistance, Article, Non-adherence, Diseases of the respiratory system, 03 medical and health sciences, 0302 clinical medicine, Pulmonary tuberculosis, Internal medicine, Inhalants, Medicine, 030212 general & internal medicine, education, education.field_of_study, RC705-779, Inhalation, business.industry, medicine.disease, Drug-delivery, Treatment, Infectious Diseases, Pill, business |
| الوصف: | Highlights • India shares the highest burden of TB & MDR-TB cases in the world. • Currently, pills/injections are two modes of treatment available for TB patients. • Inhalants could be preferred and acceptable drug delivery method among TB patients. • Exploration of diverse drug delivery options for TB patients is recommended. Background Presently, pills and injections are the two modes of therapeutic treatment available for tuberculosis (TB) patients. Many researchers have hypothesized inhalation drug delivery for reducing treatment times and possibly limiting the insurgence of drug resistance. This study was aimed at identifying and assessing the preferences of inhalation therapy over injections/pills among pulmonary TB patients. Method Cross-sectional study design was used and a sample of 477 participants were recruited at selected three Directly Observed Treatment Short-Course (DOTS) centers in Bhiwandi city. Data was collected through self-reported questionnaire. Descriptive statistics were reported, and binomial regression models were applied for data analysis. Results The preference of inhalants over pills/injections among pulmonary TB patients was significantly associated with clinical characteristics. The patients who underwent treatment for more than 1 year were 1.7 times more likely to prefer inhalants over pills/injections when compared with treatment duration of less than 1 year. Similarly, patients taking five or more pills/day were 1.7 times more likely to prefer inhalants over pills/injections when compared with patients taking 1–4 pills per day. Conclusion The study results signify that inhalants could be an acceptable method of drug delivery in this population of TB patients. Diverse drug delivery options for TB patients may greatly contribute towards TB treatment adherence. |
| اللغة: | English |
| تدمد: | 2405-5794 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd6c6ed8cb65eda7cb28ae823fdf3e9Test http://europepmc.org/articles/PMC8095169Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7dd6c6ed8cb65eda7cb28ae823fdf3e9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 24055794 |
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