The Dutch Pancreas Biobank Within the Parelsnoer Institute: A Nationwide Biobank of Pancreatic and Periampullary Diseases
| العنوان: | The Dutch Pancreas Biobank Within the Parelsnoer Institute: A Nationwide Biobank of Pancreatic and Periampullary Diseases |
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| المؤلفون: | Ignace H. J. T. de Hingh, Lodewijk A.A. Brosens, Johanna W. Wilmink, Arantza Farina Sarasqueta, M. Liem, Marin Strijker, L. Bengt van Rijssen, Marja A. Boermeester, Jony van Hilst, Geert Kazemier, Mustafa Suker, Vincent E de Meijer, Bert A. Bonsing, Arja Gerritsen, Olivier R. Busch, Marc G. Besselink, Hjalmar C. van Santvoort, Erwin van der Harst, Judith H E Verhagen, Joanne Verheij, Cornelis J. H. M. van Laarhoven, I. Quintus Molenaar, Paul Fockens, Ronald M. van Dam, Clément J. Huysentruyt, Hanneke W. M. van Laarhoven, Casper H.J. van Eijck, Maarten F. Bijlsma, Roos Wennink, Jeanin E. van Hooft, Michael F. Gerhards, Marco J. Bruno, Frederike Dijk, Joost M. Klaase, Bas Groot Koerkamp, Hein W. Verspaget |
| المساهمون: | Gastroenterology & Hepatology, Surgery, Graduate School, AGEM - Re-generation and cancer of the digestive system, AGEM - Digestive immunity, CCA - Imaging and biomarkers, AGEM - Endocrinology, metabolism and nutrition, Center of Experimental and Molecular Medicine, Radiotherapy, Pathology, Gastroenterology and Hepatology, Oncology, APH - Methodology, Groningen Institute for Organ Transplantation (GIOT), Value, Affordability and Sustainability (VALUE), Center for Liver, Digestive and Metabolic Diseases (CLDM), RS: NUTRIM - R2 - Liver and digestive health, MUMC+: MA Heelkunde (9) |
| المصدر: | Pancreas, 47, 495-501 Pancreas, 47, 4, pp. 495-501 Pancreas, 47(4), 495. Lippincott Williams and Wilkins Pancreas, 47(4), 495-501. Lippincott Williams & Wilkins Pancreas, 47(4), 495-501 Pancreas, 47(4), 495-501. Lippincott Williams and Wilkins PANCREAS, 47(4), 495-501. LIPPINCOTT WILLIAMS & WILKINS Pancreas, 47(4), 495-501. LIPPINCOTT WILLIAMS & WILKINS Strijker, M, Gerritsen, A, van Hilst, J, Bijlsma, M F, Bonsing, B A, Brosens, L A, Bruno, M J, van Dam, R M, Dijk, F, van Eijck, C H, Farina Sarasqueta, A, Fockens, P, Gerhards, M F, Groot Koerkamp, B, van der Harst, E, de Hingh, I H, van Hooft, J E, Huysentruyt, C J, Kazemier, G, Klaase, J M, van Laarhoven, C J, van Laarhoven, H W, Liem, M S, de Meijer, V E, van Rijssen, L B, van Santvoort, H C, Suker, M, Verhagen, J H, Verheij, J, Verspaget, H W, Wennink, R A, Wilmink, J W, Molenaar, I Q, Boermeester, M A, Busch, O R & Besselink, M G 2018, ' The Dutch Pancreas Biobank within the Parelsnoer Institute: A nationwide Biobank of pancreatic and periampullary diseases ', Pancreas, vol. 47, no. 4, pp. 495-501 . https://doi.org/10.1097/MPA.0000000000001018Test |
| بيانات النشر: | Lippincott Williams & Wilkins, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Endocrinology, Diabetes and Metabolism, MULTICENTER, Translational Research, Biomedical, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], PLUS GEMCITABINE, 0302 clinical medicine, Endocrinology, Bioresources, Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14], Prospective Studies, Prospective cohort study, MOLECULAR PATHOLOGY, Biological Specimen Banks, Netherlands, Academic Medical Centers, Middle Aged, OPEN-LABEL, CANCER, Biobank, Diabetes and Metabolism, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, 030211 gastroenterology & hepatology, Pancreas, Chronic pancreatitis, Ampulla of Vater, medicine.medical_specialty, Tissue and Organ Procurement, Translational research, Periampullary tumors, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Internal medicine, Pancreatic cancer, medicine, Internal Medicine, Journal Article, Humans, COHORT, Aged, LANDSCAPE, Hepatology, business.industry, General surgery, medicine.disease, Personalized medicine, RANDOMIZED-TRIAL, Pancreatic Neoplasms, Clinical research, TISSUE, Pancreatitis, business |
| الوصف: | OBJECTIVES: Large biobanks with uniform collection of biomaterials and associated clinical data are essential for translational research. The Netherlands has traditionally been well organized in multicenter clinical research on pancreatic diseases, including the nationwide multidisciplinary Dutch Pancreatic Cancer Group and Dutch Pancreatitis Study Group. To enable high-quality translational research on pancreatic and periampullary diseases, these groups established the Dutch Pancreas Biobank.METHODS: The Dutch Pancreas Biobank is part of the Parelsnoer Institute and involves all 8 Dutch university medical centers and 5 nonacademic hospitals. Adult patients undergoing pancreatic surgery (all indications) are eligible for inclusion. Preoperative blood samples, tumor tissue from resected specimens, pancreatic cyst fluid, and follow-up blood samples are collected. Clinical parameters are collected in conjunction with the mandatory Dutch Pancreatic Cancer Audit.RESULTS: Between January 2015 and May 2017, 488 patients were included in the first 5 participating centers: 4 university medical centers and 1 nonacademic hospital. Over 2500 samples were collected: 1308 preoperative blood samples, 864 tissue samples, and 366 follow-up blood samples.CONCLUSIONS: Prospective collection of biomaterials and associated clinical data has started in the Dutch Pancreas Biobank. Subsequent translational research will aim to improve treatment decisions based on disease characteristics. |
| وصف الملف: | image/pdf; application/pdf |
| تدمد: | 1536-4828 0885-3177 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdee080786fe92d4b411b9f2eae945cTest https://doi.org/10.1097/mpa.0000000000001018Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7cdee080786fe92d4b411b9f2eae945c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15364828 08853177 |
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