Dictyostelium discoideum mitochondrial DNA encodes a NADH:Ubiquinone oxidoreductase subunit which is nuclear encoded in other eukaryotes
| العنوان: | Dictyostelium discoideum mitochondrial DNA encodes a NADH:Ubiquinone oxidoreductase subunit which is nuclear encoded in other eukaryotes |
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| المؤلفون: | Robert A. Cole, Martin B. Slade, Keith L. Williams |
| المصدر: | Journal of Molecular Evolution. 40:616-621 |
| بيانات النشر: | Springer Science and Business Media LLC, 1995. |
| سنة النشر: | 1995 |
| مصطلحات موضوعية: | Mitochondrial DNA, Protein subunit, Molecular Sequence Data, Biology, Mitochondrion, MT-RNR1, DNA, Mitochondrial, Dictyostelium discoideum, Genetics, Slime mold, Animals, Dictyostelium, NADH, NADPH Oxidoreductases, Molecular Biology, Gene, Phylogeny, Ecology, Evolution, Behavior and Systematics, Paracoccus denitrificans, Electron Transport Complex I, Base Sequence, fungi, biology.organism_classification, Biological Evolution, Nuclear DNA, Cell biology, Sequence Alignment |
| الوصف: | Complex I, a key component of the mitochondrial electron transport system, is thought to have evolved from at least two separate enzyme systems prior to the evolution of mitochondria from a bacterial endosymbiont, but the genes for one of the enzyme systems are thought to have subsequently been transferred to the nuclear DNA. We demonstrated that the cellular slime mold Dictyostelium discoideum retains the ancestral characteristic of having mitochondria encoding at least one gene (80-kDa subunit) that is nuclear encoded in other eukaryotes. This is consistent with the cellular slime molds of the family Dictyosteliaceae having diverged from other eukaryotes at an early stage prior to the loss of the mitochondrial gene in the lineage giving rise to plants and animals. The D. discoideum mitochondrially encoded 80-kDa subunit of complex I exhibits a twofold-higher mutation rate compared with the homologous chromosomal gene in other eukaryotes, making it the most divergent eukaryotic form of this protein. |
| تدمد: | 1432-1432 0022-2844 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c3357379733a6f3b474f8aba02b5d1Test https://doi.org/10.1007/bf00160509Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....76c3357379733a6f3b474f8aba02b5d1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14321432 00222844 |
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