Mortality and complications after treatment of acute diabetic Charcot foot

التفاصيل البيبلوغرافية
العنوان: Mortality and complications after treatment of acute diabetic Charcot foot
المؤلفون: Rasmus Bo Jansen, Ole Lander Svendsen, Bo Jørgensen, Per Holstein, Klaus Kirketerp Møller
المصدر: Journal of diabetes and its complications. 32(12)
سنة النشر: 2018
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Diabetic neuropathy, Endocrinology, Diabetes and Metabolism, Denmark, Population, 030209 endocrinology & metabolism, Type 2 diabetes, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Diabetic Neuropathies, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, education, Aged, Retrospective Studies, education.field_of_study, Type 1 diabetes, Wound Healing, business.industry, Retrospective cohort study, Middle Aged, medicine.disease, Diabetic Foot, Diabetes Mellitus, Type 2, Acute Disease, Female, Arthropathy, Neurogenic, business, Complication, Foot (unit)
الوصف: Aims Charcot foot is a rare but disabling complication to diabetic neuropathy, and can cause permanent, limb-threatening deformities. The aim of this study was to investigate a population of patients a Charcot foot on a case-by-case basis, in order to assess the consequences of an acute Charcot foot and its complications. Methods The study was conducted a retrospective study of patients admitted to the Copenhagen Wound Healing Center between 1996 and 2015 with the diagnosis of Charcot foot (DM14.6) and diabetes mellitus type 1 or 2 (DE10.X and DE11.X). Physical and electronic records were used, and compared to data from the Danish Diabetes Registry. Results In total 392 patients were identified of which 173 were included. There were 26% with type 1 diabetes (initial HbA1c 81.7 ± 21.4 mmol/mol) and 74% with type 2 diabetes (initial HbA1c 66.5 ± 20.3 mmol/mol). Primary off-loading was with a removable walker in 95% of the cases (average off-loading time 8.3 months). The 5-year mortality was 14% with a mean survival time of 12.7 years. There was an association between lack of compliance and occurrence of foot complications, as well as between having a Charcot foot and leaving the workforce. Conclusion More patients had type 1 diabetes compared to the background population, and they had a higher HbA1c than the general population of diabetes patients. A total of 67% developed complications such as ulcers, while patients non-compliant to treatment did significantly worse than those being compliant. The 5-year mortality was low, 14%, and comparable to diabetes patients without Charcot foot.
تدمد: 1873-460X
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7528e8c5caee9014c3c863d4e124100eTest
https://pubmed.ncbi.nlm.nih.gov/30301593Test
حقوق: CLOSED
رقم الانضمام: edsair.doi.dedup.....7528e8c5caee9014c3c863d4e124100e
قاعدة البيانات: OpenAIRE