Allergen-specific immunotherapy of Hymenoptera venom allergy – also a matter of diagnosis
| العنوان: | Allergen-specific immunotherapy of Hymenoptera venom allergy – also a matter of diagnosis |
|---|---|
| المؤلفون: | Markus Ollert, Anke Graessel, Simon Blank, Carsten B. Schmidt-Weber, Maximilian Schiener |
| المصدر: | Human Vaccines & Immunotherapeutics Schiener, M, Graessel, A, Ollert, M, Schmidt-Weber, C B & Blank, S 2017, ' Allergen-specific immunotherapy of Hymenoptera venom allergy : also a matter of diagnosis ', Human Vaccines & Immunotherapeutics, vol. 13, no. 10, pp. 2467-2481 . https://doi.org/10.1080/21645515.2017.1334745Test Hum. Vaccin. Immunother. 13, 2467-2481 (2017) |
| بيانات النشر: | Informa UK Limited, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Hypersensitivity, Immediate, 0301 basic medicine, component-resolved diagnosis, Allergy, medicine.medical_treatment, Immunology, Reviews, Wasp Venoms, Venom, Biology, medicine.disease_cause, complex mixtures, Mice, 03 medical and health sciences, 0302 clinical medicine, Allergen, Immune system, Journal Article, anaphylaxis, medicine, Animals, Humans, Immunology and Allergy, hymenoptera venom, yellow jacket venom, Arthropod Venoms, Pharmacology, Clinical Trials as Topic, honeybee venom, allergen-specific immunotherapy, Hymenoptera venom allergy, Specific immunotherapy, Immunotherapy, Allergens, Immunoglobulin E, insect venom hypersensitivity, venom-specific immunotherapy, medicine.disease, Polistes venom, ddc, Bee Venoms, 030104 developmental biology, 030228 respiratory system, Desensitization, Immunologic, Polistes Venom, Allergen-specific Immunotherapy, Anaphylaxis, Component-resolved Diagnosis, Honeybee Venom, Hymenoptera Venom, Insect Venom Hypersensitivity, Venom-specific Immunotherapy, Wasp Venom, Yellow Jacket Venom, Quality of Life, wasp venom |
| الوصف: | Stings of hymenoptera can induce IgE-mediated hypersensitivity reactions in venom-allergic patients, ranging from local up to severe systemic reactions and even fatal anaphylaxis. Allergic patients' quality of life can be mainly improved by altering their immune response to tolerate the venoms by injecting increasing venom doses over years. This venom-specific immunotherapy is highly effective and well tolerated. However, component-resolved information about the venoms has increased in the last years. This knowledge is not only able to improve diagnostics as basis for an accurate therapy, but was additionally used to create tools which enable the analysis of therapeutic venom extracts on a molecular level. Therefore, during the last decade the detailed knowledge of the allergen composition of hymenoptera venoms has substantially improved diagnosis and therapy of venom allergy. This review focuses on state of the art diagnostic and therapeutic options as well as on novel directions trying to improve therapy. |
| وصف الملف: | application/pdf |
| تدمد: | 2164-554X 2164-5515 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749114d1a964cfbaeaf98126b2c905f7Test https://doi.org/10.1080/21645515.2017.1334745Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....749114d1a964cfbaeaf98126b2c905f7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 2164554X 21645515 |
|---|