Use of selective arterial secretin injection test to guide surgery in patients with Zollinger-Ellison syndrome
| العنوان: | Use of selective arterial secretin injection test to guide surgery in patients with Zollinger-Ellison syndrome |
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| المؤلفون: | Masayuki Imamura, Kiyoyuki Takahashi |
| المصدر: | World Journal of Surgery. 17:433-438 |
| بيانات النشر: | Springer Science and Business Media LLC, 1993. |
| سنة النشر: | 1993 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Pancreatic disease, Secretin, Zollinger-Ellison Syndrome, medicine, Humans, Pancreas, business.industry, Middle Aged, medicine.disease, digestive system diseases, Zollinger-Ellison syndrome, Surgery, Cardiac surgery, Pancreatic Neoplasms, medicine.anatomical_structure, Injections, Intra-Arterial, Cardiothoracic surgery, Gastrinoma, Duodenum, Female, business, Abdominal surgery |
| الوصف: | It is often difficult to localize gastrinomas in patients with Zollinger-Ellison syndrome (ZES). We have developed a new useful method, the selective arterial secretin injection test (SASI test), for localizing gastrinomas in patients with ZES. The SASI test first determines the arteries feeding the gastrinomas and then locates the gastrinomas. In 12 patients with ZES, the SASI test clearly localized the gastrinomas, while results obtained with computed tomography or portal venous blood sampling had a positive predictability of less than 10%. Following localization with the SASI test, curative resection of gastrinomas was successfully performed on 7 patients who consented to the operation. Each of 3 patients had one duodenal submucosal microgastrinoma and one or more metastatic lymph node; the other 4 patients had 2 to 10 microgastrinomas or large gastrinomas in the duodenum or the pancreas. All 7 patients, who exhibited negative responses with a postoperative secretin test, have been completely cured from 3 months to 4 years postoperatively. The usefulness of the SASI test for preoperative evaluation is demonstrated by the fact that it gives a 100% positive predictability rate as well as a 100% negative predictability rate. Hence the SASI test precisely locates functioning gastrinomas. |
| تدمد: | 1432-2323 0364-2313 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745efa7a02c26ac1d59cfb6ecf6f44c5Test https://doi.org/10.1007/bf01655100Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....745efa7a02c26ac1d59cfb6ecf6f44c5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14322323 03642313 |
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